Anxiety Supplements for Adults

(Note: The term ‘anxiety’ used in this article only refers to non-General Anxiety Disorder  anxiety and does not promote supplement products to address any anxiety disorders. Please consult with your healthcare provider before including these supplements in your diet.)

Article Summary:

  • Supplements can help support a healthy response to stress and mild anxiety in adults.
  • Supplements of this nature work in different ways — promoting endocannabinoid production, supporting the gut microbiome, or eliminating free radicals to influence neurological health.
  • Tesseract’s supplement formulations for mental wellness utilize a proprietary nutrient delivery technology to enable optimal absorption of active nutrients.

The fight or flight response is our body’s built-in mechanism to protect us from threat or danger. Anxiety is a feeling of unease, the fight or flight response in the form of worry or fear, that can be mild or severe. So, can supplements help ease anxiety? There is no straightforward answer to it. Anxiety can present very differently in affected individuals. While some may respond well to traditional medications, alternative approaches such as supplements can serve as a suitable alternative for those who want to avoid the side effects of conventional medicines.   

Supplements, such as those containing anandamide, can help enhance endocannabinoid production in the body to support a healthy response to stress and anxiety in adults. Other supplements, including those promoting gastrointestinal health, help maintain the gut flora that indirectly helps alleviate anxiety. 

Below, we discuss some supplement formulations that support gastrointestinal (GI) and neurological health to help address anxiety.      

Mental Wellness Supplements for Adults: An Overview

Our body’s endocannabinoid signaling regulates emotional behavior, mood, and stress responsivity. Several studies have highlighted the correlation between anxiety and endocannabinoid signaling. Gut health and oxidative stress also influence responses to anxiety. Let’s look at the relation between anxiety, endocannabinoid signaling, gut health, and oxidative stress. 

  • Anxiety and endocannabinoid signaling: Preclinical and clinical studies have established the role of cannabinoids in interfering with anxiety responses. Endocannabinoids, such as anandamide (AEA) and 2-arachidonoyl glycerol (2-AG), are produced by the body and are critical components of the endocannabinoid system (ECS). Enhanced anandamide signaling (through inhibiting the enzyme fatty acid amide hydrolase (FAAH)) is known1 to buffer against the effects of stress and address behavioral signs of anxiety. 
  • Anxiety and gut health: The gut-brain axis is a bi-directional network connecting the gastrointestinal system and central nervous system. The gut-brain axis lets the brain influence intestinal activities, and the gut affects mood, cognition, and mental health. 

Anxiety is closely linked2 to functional GI disruptions associated with the alterations of the gut microbiome. Supplements such as butyric acid or butyrate enhance the endogenous production of this short-chain fatty acid (SCFA) in the intestine to stabilize the gut microbiome and promote neurological health.  

  • Anxiety and oxidative stress: Oxidative stress is the imbalance between the production of reactive oxygen species (or free radicals) and the ability of the body’s defense mechanism to detoxify these reactive products. 

Recent findings3 have established the potential role of oxidative stress in triggering anxiety and emotional distress. In animal studies, the expression of glutathione reductase I and glyoxalase I, the genes involved in antioxidative metabolism, is closely associated with anxiety-related phenotypes. Supplements such as glutathione help modulate oxidative stress and support optimal cellular and neurological functions. 

The following table highlights a few supplements for anxiety in adults developed by Tesseract Medical Research.  

Anxiety Supplements for Adults

AnaQuell®

The revolutionary and hypoallergenic formulation is developed for enhanced anandamide absorption. 

  • AnaQuell® contains anandamide and L-citrulline to promote a healthy response to stress, mood changes, mild anxiety, and trauma. 
  • Anandamide, via cannabinoid receptor activation, has been shown to exert an inhibitory effect on mild anxiety.
  • L-citrulline helps enhance blood flow and nutrient delivery to the brain, beneficially impacting the body’s response to stress and mild anxiety. 

ProButyrate®

The natural butyric acid proprietary complex is developed to increase SCFA supplementation and stabilize the gut microbiome. 

  • Tesseract’s nutrient delivery system helps overcome the palatability, bioavailability, and absorption challenges associated with butyric acid.
  • ProButyrate® makes obsolete the conventional method of butyrate supplementation through sodium butyrate enema or oral ingestion of butyrate mineral salts.
  • ProButyrate® helps support a healthy inflammatory response in the gut to support gastrointestinal and neurological health. 

SafeCell®

The acetylated form of oral glutathione supplementation is developed for enhanced absorption and efficacy. 

  • Glutathione is traditionally a difficult-to-absorb molecule through the oral route. 
  • Tesseract’s proprietary technology enables targeted delivery of glutathione molecules at the desired point in the intestinal tract. 
  • The formulation helps support natural detoxification pathways, neutralize free radicals, and support healthy aging and neurological health.  

Tesseract’s revolutionary CyLoc® – DexKey® nutrient delivery nanotechnology optimizes the solubility and absorption of active nutrients, encasing them in a dextrin fiber matrix and releasing them at the desired point in the intestinal tract. The smart delivery system enables unprecedented absorption of active nutrients — one palatable molecule at a time, to make their benefits a therapeutic reality. 

Including Supplements for Anxiety in Your Diet

The safety profile of the active ingredients present in these anxiety supplement formulations is well-established. However, it is always recommended to consult your healthcare practitioner before including an any supplement in your diet to rule out the risks for potential contradictions and adverse effects, if any. 

The power of Tesseract supplements lies in enhancing palatability, maximizing absorption and bioavailability, and nano -dosing multiple nutrients in a single, highly effective capsule. Shop products on our website and learn more about how they can help support neurological health.*

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Citations:

1Morena, Maria et al. The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 39,7 (2019): 1275-1292. doi:10.1523/JNEUROSCI.2251-18.2018

2Appleton, Jeremy. Integrative medicine (Encinitas, Calif.) vol. 17,4 (2018): 28-32.

3Bouayed, Jaouad et al. Oxidative medicine and cellular longevity vol. 2,2 (2009): 63-7. doi:10.4161/oxim.2.2.7944

Al Czap, Founder | Tesseract

Al Czap has more than four decades of professional experience in preventative medicine. He founded Thorne Research in 1984 (sold in 2010) and he published Alternative Medicine Review for 17 years beginning in 1996. AMR was a highly acclaimed, peer-reviewed, and indexed medical journal. Al was the first to recognize the need for hypoallergenic ingredients and to devise methods of manufacture for and delivery of hypoallergenic products to underserved patient populations. His work has greatly impacted those with impaired immune and digestive systems and compromised health due to environmental exposures.

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