Fish oil supplements in a bowl

Best Heart Health Supplements

Article Summary:

  • A balanced diet rich in micro- and macro-nutrients and a healthy lifestyle are critical for promoting cardiovascular health.
  • However, getting the required nutrients from your diet alone can be difficult. That is why you should consider taking a heart health supplement.
  • Tesseract’s proprietary nutrient delivery nanotechnology enables the optimal absorption of active nutrients to enhance the efficacy of heart health supplements.*  

How healthy is your heart? Several factors, including stress, anxiety, poor nutrition, and a sedentary lifestyle, can contribute to cardiovascular disorders. A healthy diet and regular exercise has been shown to help prevent cardiovascular events. In addition, a heart health supplement can fill nutritional gaps and help maintain healthy cardiovascular function.* 

Below, we discuss the best heart health supplements, how they provide cardiovascular benefits, and why you should include an advanced heart health supplement in your diet. 

Best Heart Health Supplements: An Overview 

A balanced diet rich in fruits, vegetables, beans, legumes, whole grains, and lean proteins can lower cholesterol, manage blood sugar, and support a healthy weight, thereby promoting optimal cardiovascular function. However, getting the required nutrients through diet alone can be challenging for many. A heart health support supplement can be a helpful addition to a healthy diet. 

The following table highlights some of the best heart health nutrients and how they exert cardiovascular benefits. 

Best Heart Health Nutrients
Nutrient Cardiovascular benefits
Omega – 3 fatty acids
  1. Omega-3 fatty acids, the key constituent of fish oil supplements, help maintain the normal inflammatory response in cardiac cells.1
  2. Omega-3 fatty acids enhance endothelial function by promoting the release of nitric oxide from endothelial cells.2 
  3. Studies suggest that omega-3 fatty acids help lower serum levels of triglycerides, enhance flow-mediated arterial dilation, and promote the heart’s mechanical function.3  
Folate
  1. The naturally occurring form of vitamin B9, aka folate, is associated with healthy vascular reactivity, allowing for normal dilation and constriction of the blood vessels.4 
  2. Folate acts as an essential co-factor in homocysteine-methionine metabolism. Elevated homocysteine levels have been associated with plaque buildup in arteries.5  
Vitamin D
  1. Low blood levels of vitamin D can increase the chances of adverse cardiovascular conditions.6 
  2. The vitamin D receptor is expressed in cells throughout the vascular system. Vitamin D plays a role in inhibiting vascular smooth muscle proliferation and vascular calcification.7 
  3. Vitamin D helps regulate blood pressure volume and glucose metabolism, limiting adverse inflammatory responses in the cardiovascular system.8,9
Potassium
  1. Low or high in potassium levels have been linked to irregular heartbeat.10 
  2. Potassium has been found to help maintain normal blood pressure levels.11 
Magnesium
  1. Magnesium activates12 the adenosine triphosphatase (ATPase) class of enzymes, which is essential for cell membrane functioning. Magnesium deficiency is associated with less polarized membrane potential, causing irregular heartbeat. 
  2. Magnesium is a critical co-factor for the healthy functioning of the cardiac mitochondria (the cellular organelles responsible for producing the energy needed for cardiac muscular contraction and relaxation).13 
  3. Magnesium protects against potassium loss in cardiac mitochondria which is critical for maintaining a healthy heart rate and rhythm.14 
Lipoic acid
  1. Lipoic acid supports the functioning of vascular endothelium by increasing the bioavailability of endothelium-derived nitric oxide (NO).15 
  2. The antioxidant properties of lipoic acid limit age-related oxidative stress on heart health.16 
Coenzyme Q10
  1. CoQ10’s antioxidant properties inhibit the oxidation of low-density lipoproteins, helping to maintain a normal blood flow in the arteries.17 
  2. CoQ10 down-regulates the activity of proinflammatory cytokines — the signaling molecules secreted by immune cells that promote inflammation.18 CoQ10 also protects the inner lining of arteries from adverse inflammatory reactions.19 
  3. CoQ10 protects against oxidative stress to the heart.20 

Quercetin
  1. Quercetin supplementation has been shown to help maintain normal blood pressure levels.21 
  2. Quercetin plays a role in inhibiting the expression of specific cell surface proteins (adhesion molecules) to help maintain healthy arteries.22 

When considering heart health supplements that contain the above nutrients, it is important to note the efficacy of the formulation, which is determined by the absorption and bioavailability of the nutrients. 

Including an Advanced Heart Health Supplement in Your Diet 

Tesseract Medical Research has developed a range of heart health supplements with trusted nutrients sourced from potent botanical extracts. Tesseract’s proprietary CyLoc® – DexKey® nutrient delivery nanotechnology ensures targeted delivery of nutrients for optimal absorption and bioaccessibility.*

The CyLoc® technology encases each nutrient molecule to protect it from early degradation during its transit through the stomach. The accompanying DexKey® reactors release each molecule at the desired point in the intestinal tract for maximum absorption. The unprecedented absorption of beneficial nutrients ranks Tesseract’s formulations among the best heart health supplements.

The power of Tesseract supplements lies in enhancing palatability, maximizing absorption and bioavailability, and micro-dosing of multiple nutrients in a single, highly effective capsule. Shop products on our website and learn more about how they can help support your cardiovascular health*  

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Citations

1Duda MK, O’Shea KM, Tintinu A, et al. Cardiovasc Res. 2009;81(2):319-327. doi:10.1093/cvr/cvn310

2Yamagata K. Curr Pharm Des. 2020;26(30):3652-3666. doi:10.2174/1381612826666200403121952

3Mohebi-Nejad A, Behnood B. Omega-3 supplements and cardiovascular diseases. Tanaffos vol. 13,1 (2014):6-14.

4Ganguly P, Sreyoshi FA. Nutrition Journal vol. 14 6. 10 Jan. 2015, doi:10.1186/1475-2891-14-6

5Duell PB, Malinow MR. Curr Opin Lipidol. 1997;8(1):28-34. doi:10.1097/00041433-199702000-00007

6Leu M, Giovannucci E. Best Pract Res Clin Endocrinol Metab. 2011;25(4):633-646. doi:10.1016/j.beem.2011.04.001

7Skibska B, Goraca A. Oxidative Medicine and Cellular Longevity vol. 2015 (2015): 313021. doi:10.1155/2015/313021

8Li YC, Qiao G, Uskokovic M, Xiang W, Zheng W, Kong J. J Steroid Biochem Mol Biol. 2004;89-90(1-5):387-392. doi:10.1016/j.jsbmb.2004.03.004

9Garbossa SG, Folli F. Rev Endocr Metab Disord. 2017;18(2):243-258. doi:10.1007/s11154-017-9423-2

10Ravn Jacobsen M, Jabbari R, Glinge C, et al. J Am Heart Assoc. 2020;9(4):e014160. doi:10.1161/JAHA.119.014160

11Houston MC. Curr Hypertens Rep. 2011;13(4):309-317. doi:10.1007/s11906-011-0197-8

12DiNicolantonio JJ, et al. Open Heart vol. 5,2 e000775. 1 Jul. 2018, doi:10.1136/openhrt-2018-000775

​​13Rabanal-Ruiz Y, et al. Antioxidants (Basel, Switzerland) vol. 10,5 755. 10 May. 2021, doi:10.3390/antiox10050755

14Chakraborti S, Chakraborti T, Mandal M, Mandal A, Das S, Ghosh S. Mol Cell Biochem. 2002;238(1-2):163-179. doi:10.1023/a:1019998702946

15Bhaskar S, Sudhakaran PR, Helen A. Cell Immunol. 2016;310:131-140. doi:10.1016/j.cellimm.2016.08.011

16Park S, Karunakaran U, Jeoung NH, Jeon JH, Lee IK. Curr Med Chem. 2014;21(32):3636-3645. doi:10.2174/0929867321666140706141806

17Rabanal-Ruiz, Yoana et al. Antioxidants (Basel, Switzerland) vol. 10,5 755. 10 May. 2021, doi:10.3390/antiox10050755

18Schmelzer C, Lorenz G, Lindner I, et al. Biofactors. 2007;31(1):35-41. doi:10.1002/biof.5520310104

19Tsai KL, Huang YH, Kao CL, et al. J Nutr Biochem. 2012;23(5):458-468. doi:10.1016/j.jnutbio.2011.01.011

20Liang S, Ping Z, Ge J. Oxid Med Cell Longev. 2017;2017:9863181. doi:10.1155/2017/9863181

21Serban MC, Sahebkar A, Zanchetti A, et al. J Am Heart Assoc. 2016;5(7):e002713. Published 2016 Jul 12. doi:10.1161/JAHA.115.002713

22Bhaskar S, Sudhakaran PR, Helen A. Cell Immunol. 2016;310:131-140. doi:10.1016/j.cellimm.2016.08.011

Al Czap, Founder | Tesseract

Al Czap has more than four decades of professional experience in preventative medicine. He founded Thorne Research in 1984 (sold in 2010) and he published Alternative Medicine Review for 17 years beginning in 1996. AMR was a highly acclaimed, peer-reviewed, and indexed medical journal. Al was the first to recognize the need for hypoallergenic ingredients and to devise methods of manufacture for and delivery of hypoallergenic products to underserved patient populations. His work has greatly impacted those with impaired immune and digestive systems and compromised health due to environmental exposures.

The advanced formulations based on our revolutionary, patented, and patent-pending technology are only available through Tesseract. No other medical, pharmaceutical, or supplement company is licensed to utilize our proprietary technology.
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
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