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Best Immune Supplements

Article Summary:

  • Vitamins, minerals, and specific botanicals support healthy immune function and strengthen the body’s defense system.*

  • Certain compounds, such as zinc and quercetin, have naturally poor absorption, which can negatively impact the efficacy of immune supplement formulations.

  • Tesseract’s proprietary nutrient delivery nanotechnology enhances the solubility and absorption of nutrient molecules for improved bioaccessibility for the immune system .*

The immune system is critical in protecting the body against pathogens (bacteria, parasites, viruses, and fungi), harmful pollutants, unwanted cellular changes and undesirable cellular growth that can adversely impact various body functions. The immune system, which is vital to the overall functioning of your body, requires the regular intake of adequate amounts of vitamins, minerals, and specific plant-derived compounds that exert antioxidant and immune-supporting effects.

Below, we discuss some of the best immune supplements, their benefits, and why you should include an advanced immune supplement formulation with your diet.  

Best Immune Supplements — An Overview

If you do not receive an adequate amount of specific vitamins and minerals through your regular diet, then it can compromise your immune function. A deficiency of certain vitamins and minerals has been linked to altered immune responses.1 The following table highlights some of the best immune supplements — vitamins C and D, zinc, and quercetin — that should be in your diet, either in the form of food or as supplements. 

Some of the Best Immune Supplements to Support Your Health

  • Vitamin C:

  • Vitamin C is one of the most critical micronutrients for supporting immune function.*

  • White blood cells (key components of the immune system) rely on vitamin C to carry out their immune function as they accumulate vitamin C up to 100 times greater than that of the surrounding plasma (the liquid part of the blood).

  • Vitamin C supports most aspects of immune function, including innate and adaptive immune functions.3 

  • As an antioxidant, vitamin C protects immune cells from reactive oxygen species (ROS) produced during an immune response.4  

  • Vitamin D:

  • Vitamin D inhibits B-cell proliferation, differentiation, and immunoglobulin secretion, thereby decreasing the production of harmful inflammatory cytokines and adverse immune responses.5 

  • Zinc: 

  • Zinc is involved in regulating pathways in both innate and adaptive immune responses.6

  • Zinc protects the natural tissue barriers in the body (such as the cells lining the respiratory tract) and maintains the function of the immune and antioxidant systems.7 

  • Zinc acts as an antioxidant by limiting oxidative stress and the production of inflammatory cytokines.8

  • Quercetin:

  • Quercetin, a flavonoid derived from various plants, is an antioxidant that modulates various cell signaling pathways to limit the production of pro-inflammatory cytokines.

  • Quercetin exerts a stabilizing effect on mast cells, a type of immune cell that releases histamine  (a signaling chemical that triggers adverse allergic responses).10 

  • Quercetin helps maintain a balance between immune cells, particularly T-helper cells (Th1/Th2), thereby promoting a healthy immune response.11 

  • Quercetin down-regulates adverse immune responses by inhibiting the production of leukotriene — an inflammatory mediator that activates immune cells.12

It is worth noting that because high amounts of immune supplements can cause side effects, you should always consult with your healthcare provider before including an immune supplement in your diet. 

But what are the best immune supplement formulations available over the counter? To promote healthy immune function, you should consider an advanced immune supplement with enhanced absorption and bioaccessibility.  

Including An Advanced Immune Supplement in Your Diet

Tesseract Medical Research has developed various nutritional supplements that support healthy immune function. QuerciSorb Immunophore SR® is a unique quercetin supplement formulated for optimal solubility and absorption. The formulation contains some of the best immuno-supportive nutrients — vitamins C and D, zinc, and quercetin for effective immune support.* 

The challenge with most immune-enhancing nutrients, such as zinc and quercetin, is they are not well-absorbed naturally. Tesseract’s groundbreaking CyLoc® – DexKey® nutrient delivery nanotechnology enables optimal absorption of active nutrients through the gut wall. The CyLoc® technology encases nutrient molecules, maintaining their integrity during the transit through the stomach. The accompanying DexKey® reactors release each molecule at the desired point in the intestinal tract for maximum absorption. 

Additionally, QuerciSorb Immunophore SR’s nutrients are delivered in a sustained-release format to support healthy immune function all day.* These features of Tesseract’s supplement formulation make it one of the best commercially available immune supplements.

The power of Tesseract supplements lies in enhancing palatability, maximizing absorption and bioaccessibility, and micro-dosing multiple nutrients in a single, highly effective capsule. Shop products on our website and learn more about how they can help support your immune health.* 

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Citations:

1Gombart, Adrian F et al. Nutrients vol. 12,1 236. 16 Jan. 2020, doi:10.3390/nu12010236

2Moore A, Deepesh K. Cureus vol. 15,1 e33740. 13 Jan. 2023, doi:10.7759/cureus.33740

3Carr AC, Maggini S. Nutrients. 2017;9(11):1211. Published 2017 Nov 3. doi:10.3390/nu9111211

4Kesarwani P, Murali AK, Al-Khami AA, Mehrotra S. Antioxid Redox Signal. 2013;18(12):1497-1534. doi:10.1089/ars.2011.4073

5Aranow C. Journal of Investigative Medicine: the official publication of the American Federation for Clinical Research vol. 59,6 (2011):881-886. doi:10.2310/JIM.0b013e31821b8755

6Prasad AS. Molecular Medicine (Cambridge, Mass.) vol. 14,5-6 (2008):353-357. doi:10.2119/2008-00033.Prasad

7Luan, Rumei et al. European journal of clinical nutrition vol. 77,4 (2023): 427-435. doi:10.1038/s41430-022-01191-6

8Jarosz, Magdalena et al. Inflammopharmacology vol. 25,1 (2017): 11-24. doi:10.1007/s10787-017-0309-4

9Ahn, Hye In et al. Journal of microbiology and biotechnology vol. 33,4 (2023): 430-440. doi:10.4014/jmb.2208.08034

10Li Y, et al. Nutrients vol. 8,3 167. 15 Mar. 2016, doi:10.3390/nu8030167

11Tanaka, Yoshihito et al. Medicines (Basel, Switzerland) vol. 7,8 46. 30 Jul. 2020, doi:10.3390/medicines7080046

12Jafarinia, Morteza et al. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology vol. 16 36. 14 May. 2020, doi:10.1186/s13223-020-00434-0

Al Czap, Founder | Tesseract

Al Czap has more than four decades of professional experience in preventative medicine. He founded Thorne Research in 1984 (sold in 2010) and he published Alternative Medicine Review for 17 years beginning in 1996. AMR was a highly acclaimed, peer-reviewed, and indexed medical journal. Al was the first to recognize the need for hypoallergenic ingredients and to devise methods of manufacture for and delivery of hypoallergenic products to underserved patient populations. His work has greatly impacted those with impaired immune and digestive systems and compromised health due to environmental exposures.

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