A woman browsing dietary supplements in a pharmacy aisle.

Best Supplement Stack for Overall Health and Wellness

Article Summary:

  • Supplement stacks are developed to cater to an individual’s specific nutritional support needs.
  • It is always recommended to consult with your health-care provider before considering including a supplement stack in your diet.
  • A supplement stack should contain formulations that optimize the absorption and bioavailability of active nutrients in the stack. 
  • Tesseract’s proprietary nutrient delivery nanotechnology enables targeted delivery of active nutrients to optimize their absorption and bioavailability.

A supplement stack typically refers to combining two or more nutritional supplements to achieve specific training goals, to enhance athletic performance, or to better leverage a specific health and wellness goal. Supplement stacks can ensure that your body receives the vital nutrients needed to achieve the results you desire. 

Interestingly, biological aging, characterized primarily by progressive cellular deterioration, begins right after an individual’s reproductive peak. In particular, oxidative stress, along with out-of-balance inflammatory responses, contributes significantly to aging. Supplement stacks contain a wide range of nutrients that can provide antioxidant support and help maintain normal inflammatory response in cells, which limits the impact of cellular deterioration on various health functions.

This article explains the benefits of combined supplementation, highlighting several research studies, and how to build the best supplement stack for overall health and wellness with Tesseract’s innovative supplement formulations.  

The Benefits of Combined Supplementation

A supplement stack can achieve the benefits of combined supplementation. The active nutrients in multiple supplements reinforce each other, with their synergistic activity providing optimal support to various health functions. 

It is worth noting that there is no one best supplement stack for overall health and wellness, because it so much depends on an individual’s specific nutritional support requirements. Some of the most common nutrients included in supplement routines are: 

  • Vitamins: Vitamins B, C, D, E, and K, folic acid  
  • Minerals: Calcium, copper, iron, magnesium, phosphorus, selenium, zinc 
  • Botanical compounds: Berberine, curcumin, coenzyme Q10, glutathione, quercetin, thymoquinone, saw palmetto 
  • Fatty acids: Anandamide, butyric acid, lipoic acid 
  • Amino acids: Beta-alanine, casein, creatine, whey protein 

The following table summarizes several studies that highlight the benefits of combined supplementation.

Clinical Studies Highlighting the Benefits of Combined Supplementation

Combined supplementation of CoQ10 and other nutrients: A combined supplementation of coenzyme Q10, magnesium, potassium, vitamin B12, folic acid, and niacin has been found to enhance cardiac functions and influence insulin resistance.1
Combined effects of citrulline and beetroot extract: Citrulline and nitrate-rich beetroot extract are nitric oxide precursors. The combined effects of these two compounds can potentially enhance maximal and endurance strength.2
Effects of a five-ingredient nutritional supplement and resistant exercise: A randomized clinical trial on free-living elderly individuals studied the efficacy of daily intake of a five-ingredient supplement (whey, micellar casein, creatine, vitamin D3, and n-3 polyunsaturated fatty acids), in combination with home-based, unsupervised resistant exercise. The regimen was found to enhance lean mass strength, muscle-to-fat ratios, and muscle quality in the healthy older men.3

Although the benefits of combined supplementation have been established through research, before considering a supplement stack, you should focus on a balanced diet, adequate sleep, and moderate exercise.  

A Word of Caution:

Supplement stacks might not suit everyone and can cause adverse side effects if you consume the wrong mix of nutrients in too high amounts. Consult your healthcare provider before considering a supplement stack for overall health and wellness. 

Developing the Best Supplement Stack for Overall Health with Tesseract’s Formulations

Tesseract Medical Research has developed a wide range of supplement formulations with trusted nutrients, many of which have traditionally been difficult to absorb. Tesseract’s proprietary CyLoc® —DexKey® nutrient delivery nanotechnology enhances the palatability, absorption, and bioavailability of these nutrients to help achieve their therapeutic benefits. 

The following are several of Tesseract’s innovative formulations to help you build the best supplement stack for overall health and wellness. 

  • AnaQuell®: This anandamide supplement supports a healthy response to stress and mild (non-GAD) anxiety and promotes mental and emotional well-being.* 
  • AuRx®: A gold-standard medical food that contains a stabilized butyric acid complex to help alleviate behavioral changes in children with Autism Spectrum Disorder (ASD). 
  • CoQ10 Pro®: Tesseract’s proprietary nutrient delivery nanotechnology enables optimized transport and absorption of CoQ10 to promote cardiovascular health.* 
  • TetraCumin®: This curcumin supplement contains tetrahydrocurcumin — a more stabilized and bioavailable form of curcumin — to promote a healthy response to oxidative stress and help maintain normal immune function and musculoskeletal health.* 
  • SafeCell®: This formulation contains S-acetyl glutathione to enhance detoxification in the liver and promote healthy aging.* 

Tesseract’s supplement formulations assure unprecedented absorption and bioavailability of nutrients to make achieving their benefits a reality.  

The power of Tesseract supplements lies in enhancing palatability, maximizing solubility, absorption and bioavailability, and micro-dosing multiple nutrients in a single, highly effective capsule. Shop products on our website and learn more about how they support your long-term health and wellness.* 

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References: 

1Tippairote T, et al. Combined supplementation of coenzyme Q10 and other nutrients in specific medical conditions. Nutrients 2022;14,20;4383. doi:10.3390/nu14204383

2Burgos J, et al. Combined effects of citrulline plus nitrate-rich beetroot extract co-supplementation on maximal and endurance-strength and aerobic power in trained male triathletes: A randomized double-blind, placebo-controlled trial. Nutrients 2021;14,1:40.  doi:10.3390/nu14010040
3Nilsson MI, et al. A five-ingredient nutritional supplement and home-based resistance exercise improve lean mass and strength in free-living elderly. Nutrients 2020;12,8:2391.  doi:10.3390/nu12082391

Al Czap, Founder | Tesseract

Al Czap has more than four decades of professional experience in preventative medicine. He founded Thorne Research in 1984 (sold in 2010) and he published Alternative Medicine Review for 17 years beginning in 1996. AMR was a highly acclaimed, peer-reviewed, and indexed medical journal. Al was the first to recognize the need for hypoallergenic ingredients and to devise methods of manufacture for and delivery of hypoallergenic products to underserved patient populations. His work has greatly impacted those with impaired immune and digestive systems and compromised health due to environmental exposures.

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