Butyrate, a short-chain fatty acid, has recently gained significant attention for its potential role in supporting gastrointestinal health.* Butyrate, propionate, and acetate are some of the key organic acids produced in the lower intestinal tract, the result of bacterial fermentation of undigested dietary fibers and resistant starch, and to some extent, dietary and endogenous proteins.
Several studies highlight the role of butyrate in modulating immune function and supporting a healthy inflammatory response in the gastrointestinal tract.* Furthermore, there is growing evidence of butyrate’s beneficial effect on modulating brain function through the gut-brain axis.*
Low dietary fiber intake can limit the gut’s production of short-chain fatty acids, including butyrate, which can adversely affect local and systemic GI inflammatory responses. That’s why it‘s important to have a diet full of butyrate-rich foods. Incorporating a butyrate supplement is an effective alternative to supporting a healthy gut microbiota.*
The colonic microbiota is one of the body’s most metabolically active areas. Short-chain fatty acids contribute up to 60-70% of the energy required by colonic epithelial cells and 5-15% of the human body’s total caloric requirements.
Although butyrate is the least abundant short-chain fatty acid produced in the body, it is a major energy source for colonocytes.* Because the presence of undigested dietary fiber in the intestine and the production of butyrate are closely associated, it’s important to include high-fiber foods and butyrate-rich foods in your diet.
Fiber is defined as a complex mixture of dietary residues, primarily carbohydrates that are not digested or absorbed by the small intestine but are used instead as a food source by the colonic microbiota. The USDA recommends a daily dietary fiber intake of 25 grams for women and 38 grams for men. This includes non-starch polysaccharides, non-digestible oligosaccharides, and resistant starch.
|Butyrate-Rich Foods To Add to Your Diet|
||One of the best sources of resistant starch, raw, dried legumes contain 20-30% resistant starch by weight. Beans, peas, and lentils are also good sources of galactooligosaccharides.|
|Whole Grains||Oats, cooked and cooled rice, quinoa, wheat, rye,
and other whole grains are good sources of resistant starch.
|Fruits & Vegetables
||Fruits like watermelon, pear, blueberries, mulberries, red currants, raspberries, and figs are rich in oligosaccharides. Plantains, green bananas, and cooked, cooled potatoes are good sources of resistant starch. White onions, green cabbage, red cabbage, scallions, leeks, garlic, broccoli, and kale are also high in oligosaccharides.|
|Nuts & Seeds
Chia seeds, almonds, pistachios,
and sunflower kernels are rich
in dietary fiber.
||Moderate dairy intake: The lactic acid bacteria in foods like butter and parmesan cheese help break down milk fats and produce short-chain fatty acids, including butyrate.|
A well-balanced diet comprising these fiber-rich components promotes a healthy gastrointestinal environment. However, not every individual can tolerate the amount of fiber needed to produce the required quantity of butyrate for optimal gut function. Therefore, a butyrate supplement can be an easy, effective way to fill any nutritional gaps and increase butyric acid levels.*
When considering butyrate supplementation, it is worth noting that not all nutritional supplements are alike. The efficacy of a butyrate supplement depends on whether it is formulated to optimize the bioavailability of the active ingredient, thus leading to enhanced absorption and augmenting the gut’s butyric acid level.*
ProButyrate®, a Tesseract formula, is specially designed to restore balance and stabilize the gut microbiome.* The revolutionary CyLoc® - DexKey® nutrient delivery technology isolates and encases individual molecules of butyric acid to ensure their palatability and optimal absorption throughout the GI tract, one molecule at a time.* The hypoallergenic formula yields overall positive health benefits and helps you take control of your gut health every day.*
The power of Tesseract supplements lies in enhancing palatability, maximizing bioavailability and absorption, and micro-dosing of multiple nutrients in a single, highly effective capsule. Visit our website for more information about how Tesseract’s products can help support your gastrointestinal health.*
1 Tan J, McKenzie C, Potamitis M, et al. Adv Immunol. 2014;121:91-119. doi: 10.1016/B978-0-12-800100-4.00003-9. PMID: 24388214.