Article Summary:
- A coenzyme Q10 supplement benefits several body functions, including heart health, skin health, reproductive health, and immune function.*
- CoQ10’s naturally poor bioavailability and absorption hinder the efficacy of most CoQ10 supplements.
- Tesseract Medical Research’s advanced CoQ10 formulation utilizes a proprietary nutrient delivery nanotechnology for unprecedented absorption of CoQ10.
Coenzyme Q10 nutritional supplements come in the form of chewable tablets, capsules, oral sprays, and liquid syrups. CoQ10 supplements contain either the fully oxidized ubiquinone (CoQ10) or fully reduced ubiquinol (CoQ10H2) form of coenzyme Q10. Notably, while some studies (cite) indicate that ubiquinol generally has a higher bioavailability and absorption than ubiquinone, especially in specific populations, another study (cite the original one mentioned in references already) suggests no significant difference between the bioavailability and absorption of ubiquinone and ubiquinol supplements. Ultimately, the findings of these studies highlight that results are inconclusive and research is still emerging on the best delivery methods of CoQ10 supplements.
So, does your body need a CoQ10 supplement, particularly when CoQ10 is endogenously produced in the body? This lipid-soluble nutrient is critical in cellular energy production across the body’s tissues and organs.* Its concentration is particularly high in the organs that have high metabolism rates, such as the heart, liver, and kidneys. However, endogenous CoQ10 levels declinewith age, certain health conditions, and the use of specific medications. Supplemental CoQ10 may be beneficial in maintaining optimal CoQ10 levels, supporting overall cellular function and health.
This post discusses how a coenzyme Q10 supplement benefits various organs and why you should consider taking an advanced CoQ10 supplement for your health.
What are the Coenzyme Q10 Supplement Benefits?
The benefits of taking a coenzyme Q10 supplement are attributable to the nutrient’s antioxidant and immunomodulatory properties.* CoQ10’s antioxidant effect helps neutralize reactive oxygen species (ROS), providing protection against oxidative stress. By lowering oxidative stress and protecting cellular components, including mitochondria, it indirectly supports the function (cite) of antioxidant enzymes such as superoxide dismutase (SOD) and catalase (CAT). This contributes to an overall more effective antioxidant defense system.* The immunomodulatory properties of CoQ10 also help maintain the body’s normal inflammatory responses.*
The following table highlights the many benefits of a coenzyme Q10 supplement for various health functions in the body.
Health Function |
CoQ10 Benefits |
|---|---|
|
Heart* |
CoQ10 supplementation promotes good cardiovascular health by —
|
|
Skin* |
A CoQ10 supplement benefits skin health by —
|
|
Reproductive Health* |
Cellular mitochondrial dysfunction and oxidative stress are underlying causes of the age-related decline in female reproductive potential. Research5 suggests CoQ10 supplementation protects reproductive health against oxidative stress by —
|
|
Immune Function* |
A CoQ10 supplement promotes healthy immune function by —
|
Although the benefits of taking a CoQ10 supplement are well-established, the naturally poor absorption of CoQ10 compromises the efficacy of most CoQ10 supplements. The high molecular weight of CoQ10, its unstable ubiquinol form, its insolubility in water, and its limited solubility in lipids are the primary factors that adversely affect its bioavailability and subsequent absorption. Studies indicate that a solubilized CoQ10 formulation with an advanced nutrient delivery system displays enhanced bioavailability compared to unformulated CoQ107.
Including An Advanced CoQ10 Supplement in Your Diet
To enhance CoQ10’s bioavailability and absorption, advanced CoQ10 supplement formulations utilize novel approaches, including microcapsules, nanoparticles, nano-liposomes, solid dispersion systems, and cyclodextrin inclusion compounds. Encasing CoQ10 molecules with cyclodextrins is particularly effective in enhancing solubility.
CoQ10 Pro® is an advanced CoQ10 supplement developed by Tesseract Medical Research. CoQ10 Pro’s innovative formulation utilizes Tesseract’s proprietary CyLoc® – DexKey® nutrient delivery nanotechnology for optimal absorption of CoQ10 molecules in the intestinal tract. Tesseract’s CyLoc® technology encases individual CoQ10 molecules in its smart delivery system. The accompanying DexKey® reactors release CoQ10 molecules at the desired point in the intestinal tract for maximum absorption.
The resulting unprecedented absorption enables micro-dosing of the formulation — using the active nutrient in a lesser amount than previously required to increase circulating amounts of CoQ10 and to achieve coenzyme Q10 supplement benefits.*
The power of Tesseract supplements lies in enhancing palatability, maximizing absorption and bioavailability, and micro-dosing a nutrients in a single, highly effective capsule. Shop products on our website and learn more about how they can help support cardiovascular health..*
1Mantle D, Dybring A. Antioxidants (Basel, Switzerland) vol. 9,5 386. 5 May. 2020, doi:10.3390/antiox9050386
2Zhang Y, et al. Frontiers in Pharmacology vol. 13 936233. 14 Jul. 2022, doi:10.3389/fphar.2022.936233
3Sharifi N, et al. Current Pharmaceutical Design vol. 24,23 (2018):2729-2742. doi:10.2174/1381612824666180406104516
4Knott A, et al. BioFactors (Oxford, England) vol. 41,6 (2015):383-390. doi:10.1002/biof.1239
5Xu Y, et al. Reproductive Biology and Endocrinology: RB&E vol. 16,1 29. 27 Mar. 2018, doi:10.1186/s12958-018-0343-0
6Mantle D, et al. Antioxidants (Basel, Switzerland) vol. 10,5 759. 11 May. 2021, doi:10.3390/antiox10050759
7Sood, Brittany, et al. StatPearls – NCBI Bookshelf, 30 Jan. 2024,
