Summary:
- A depleting Coenzyme Q10 level is associated with oxidative stress that adversely affects the optimal functioning of cardiac cells.*
- The bioenergetics and antioxidant properties of Coenzyme Q10 limit the toxic effects of free radicals on heart tissues and heart muscles.*
- Tesseract’s CoQ10 Pro® is uniquely formulated to address the common bioavailability and absorption challenges of CoQ10 in the body and promote cardiovascular health.*
The mitochondrial enzyme Coenzyme Q10 (CoQ10) is at the core of cellular energy production and hence, considered critical for cells with high energy requirements, such as cardiac cells.* CoQ10 distribution is not uniform among different organs and its highest concentration is observed in the heart. Several research studies have established the potential role of CoQ10 in enhancing cellular bioenergetics to support the optimal functioning of the heart.*
Below, we discuss some of the key Coenzyme Q10 benefits for the heart and why you should include a CoQ10 nutritional supplement in your diet to promote your cardiovascular health.*
Coenzyme Q10 Benefits for Heart Health*
Coenzyme Q10 is a fat-soluble molecule that acts as an electron carrier in mitochondria and as a coenzyme for mitochondrial enzymes. It is also an antioxidant that protects cardiac cells from the harmful effects of Reactive Oxygen Species (ROS).* Emerging data suggests that free radical-mediated oxidative stress is one of the key reasons for common cardiac pathologies. The oxidation of low-density lipoprotein (LDL) by free radicals is considered a critical factor predisposing them to uptake into the vascular wall, resulting in various heart conditions. Owing to its bioenergetics and antioxidant properties, CoQ10 may help limit the toxic effects of free radicals on cardiac cells and promote heart health.*
The following table highlights Coenzyme Q10’s benefits for the heart and its potential role in protecting against cardiac pathologies.*
| CoQ10 Benefits for Heart Health | |
| Inhibits LDL oxidation* | Because CoQ10’s antioxidant properties1 inhibit the oxidation of low-density lipoproteins, it has a preventative benefit relative to the thickening or hardening of the arteries.* |
| Lowers proinflammatory cytokines level* | A number of heart conditions are associated with elevated levels of proinflammatory cytokines (IFN-γ, IL-1β, IL-6, and TNF-α) that can have detrimental effects on the inner lining of the arteries. CoQ10 helps down-regulate2 the activity of these proinflammatory cytokines.* |
| Enhancing exercise tolerance* | 60-200 mg daily CoQ10 intake by individuals suffering from heart conditions has been found3 to enhance exercise tolerance.* |
| Stabilizing myocardial calcium-dependent ion channels* | Emerging research shows4 that CoQ10 is a cellular membrane stabilizer, helping to stabilize the mitochondrial calcium-dependent ion channels of heart muscle.* This mechanism of action helps limit cellular energy depletion and enhances the contractile function of the heart.* |
| Maintaining vascular suppleness* | Because CoQ10 can limit the accumulation of oxidized LDL in the arteries, it helps maintain vascular suppleness.* CoQ10 helps eliminate the source of ROS in the vascular system, thereby enhancing the level of nitric oxide (NO) to promote vasodilation.* |
Because CoQ10 supports heart health through various mechanisms, its deficiency is associated with a wide range of cardiac issues. A depleting level of endogenous CoQ10 with age can trigger oxidative stress that impairs mitochondrial bioenergetics, resulting in lower energy production that can adversely impact the contractile function of the heart and NO levels for vasodilation.* In such cases, CoQ10 supplementation can help maintain the body’s CoQ10 level, thus supporting the optimal functioning of the heart.*
Incorporating a CoQ10 Supplement Into Your Diet
A balanced diet consisting of CoQ10-rich food, such as meat, fish, nuts, and oils helps maintain the optimal CoQ10 level in your body. However, the high molecular weight of CoQ10, along with its insolubility in water results in poor absorption that can adversely impact its beneficial effects. In contrast, nano-formulated CoQ10 supplements have shown promising results owing to their enhanced absorption and bioavailability.
Tesseract’s CoQ10 Pro® is an innovative CoQ10 nutritional supplement formula developed to support heart health.* CoQ10 Pro’s nanoformulation uses proprietary CyLoc® – DexKey® technology that solves the common challenges associated with antioxidant absorption. The CyLoc® technology isolates and encases each CoQ10 molecule in a dextrin fiber matrix. The DexKey® reactors accompany each CyLoc® molecule and release them at the desired point in the intestinal tract for maximum solubility and absorption. The unprecedented absorption of CoQ10 enables micro-dosing — the daily intake of the supplement at levels much lower than previously required. With Tesseract’s revolutionary nutrient delivery technology, CoQ10 molecules become a bioavailable therapeutic reality to promote the health of your heart.*
The power of Tesseract supplements lies in enhancing palatability, maximizing bioavailability and absorption, and micro-dosing of multiple nutrients in a single, highly effective capsule. Visit our website for more information about how Tesseract’s products support your cardiovascular health.*
Citations:
1Kumar A, et al. Role of coenzyme Q10 (CoQ10) . . . . Pharmacology & Therapeutics vol. 124,3 (2009):259-268. doi:10.1016/j.pharmthera.2009.07.003
2,3Eleawa SM, et al. Coenzyme Q10 . . . . International Journal of Physiology, Pathophysiology and Pharmacology vol. 7,1 1-13. 20 Mar. 2015
4Liang S, et al. Coenzyme Q10 regulates antioxidative stress . . . . Oxidative Medicine and Cellular Longevity vol. 2017 (2017): 9863181. doi:10.1155/2017/9863181
