Article Summary:
- Although our body naturally detoxifies on its own, certain health conditions, medications, and environmental factors can disrupt the body’s in-built detoxification pathways.
- Detox supplements contain antioxidants that can address the harmful effects of free radicals on hepatic cells and promote optimal detoxification.*
- Tesseract’s proprietary nutrient delivery nanotechnology enables the optimal absorption of active nutrients to enhance the efficacy of detox supplements.
You have probably heard of the word “detox” buzzing around the wellness space but what does it actually entail? “Detox”, or detoxification, refers to the body’s natural processes for metabolizing and eliminating toxins, primarily carried out by the liver. A healthy liver efficiently utilizes various detoxification pathways to convert toxins into water-soluble metabolites that are then eliminated from the body through the urine. But if your body can detox on its own, why consider detox supplements and how do they support detoxification?
The body’s antioxidant defense system can be compromised due to age, environment, intake of certain medications, or existing adverse health conditions, resulting in oxidative stress — a critical factor that can cause damage to liver cells and compromise detoxification efficiency. Detox supplements, formulated with ingredients such as milk thistle extracts, glutathione, ascorbic acid (vitamin C), and turmeric extracts, provide antioxidant support to address the harmful effects of free radicals on hepatic cells.*
In this article, we discuss how detox supplements work, highlight the beneficial role of the nutrients in supplement formulations, and why incorporating advanced and highly bioavailable detox supplements to your daily regimen can help optimize toxin elimination and promote better health.
How do Detox Supplements Work?
As mentioned above, detoxification supplements are designed to support the body’s natural ability to metabolize and eliminate toxins, mainly through the liver. The liver processes toxins in two key phases:
- Phase I, where harmful substances are converted into intermediate compounds, and
- Phase II, where these compounds are further transformed into water-soluble forms for easier elimination.
Ingredients such as silymarin (from milk thistle) and curcumin help protect liver cells from oxidative stress and enhance liver enzyme activity.* Glutathione, a powerful antioxidant, supports Phase I and II detoxification by neutralizing free radicals and promoting the conjugation of toxins.* Vitamin C contributes to reducing oxidative stress and regenerating other antioxidants. Together, these nutrients provide comprehensive support to maintain the liver’s efficiency.
Below is an overview of these common key ingredients found in detox supplement formulations and their therapeutic benefits to promote detoxification.
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Common Ingredients in Detox Supplements |
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Ingredient |
Therapeutic Benefits |
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Silymarin |
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Curcumin |
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Glutathione |
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Vitamin C |
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Before you consider adding detox supplements to your daily regimen, it is important to remember that eating healthy, exercising regularly, and limiting or avoiding alcohol intake are foundational steps that support the body’s detoxification processes. Also, it is recommended to consult with your healthcare provider before adding detox supplements in your diet or taking them along with any prescription medications to ensure they are safe and appropriate for your individual health needs.
Although the therapeutic benefits of these nutrients and their safety profile are well-established, their poor bioavailability and absorption can hinder the efficacy of most detox supplement formulations. A smart nutrient delivery system that enables targeted delivery of active nutrients will enhance their solubility and absorption, making them a therapeutic reality.
Including Advanced Detox Supplement Formulations in Your Diet
The proprietary CyLoc® – DexKey® nutrient delivery nanotechnology developed by Tesseract Medical Research can achieve unprecedented absorption of active nutrients in detox supplements. The CyLoc® technology encases active ingredient molecules in its dextrin fiber delivery cage. The accompanying DexKey® reactors release the active ingredient molecules at the desired point in the intestinal tract for maximum solubility and absorption.
The following detox supplements were developed by Tesseract Medical Research:
- HepatiSafe®: It contains a proprietary blend of silymarin, R-lipoic acid, glutathione, and tetrahydrocurcumin (the bioactive metabolite of curcumin) to support liver detox.* The clinically-studied nutrients delivered through a smart nutrient delivery system are optimally absorbed to promote all phases of liver detoxification, support optimal hepatic function, and maintain healthy inflammatory responses.*
- SafeCell®: The acetylated form of oral glutathione is the Tesseract detoxification solution to promote your overall health and wellness.* The supplement formulation promotes the optimal functioning of other antioxidants, downregulates oxidative stress, and supports natural detoxification pathways.*
Tesseract’s unique supplement formulations are developed following Good Manufacturing Practices (GMPs) and contain the highest-quality nutrients delivered through cutting-edge delivery systems to ensure you receive the finest quality products.
The power of Tesseract supplements lies in enhancing palatability, maximizing absorption and bioavailability, and micro-dosing multiple nutrients in a single, highly effective capsule.Shop antioxidant products oon our website and learn more about how they can support your health.*
Citations:
1Piper JT, et al. Mechanisms of . . . properties of curcumin: the effect of curcumin on glutathione linked detoxification enzymes in rat liver. The international journal of biochemistry & cell biology vol. 30,4 (1998): 445-456. doi:10.1016/s1357-2725(98)00015-6
2Agarwal R, et al. Detoxification and antioxidant effects of curcumin in rats experimentally exposed to mercury. Journal of applied toxicology: JAT vol. 30,5 (2010): 457-468. doi:10.1002/jat.1517
3Miranda CL, et al. Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells. Chemical research in toxicology vol. 22,5 (2009): 863-874. doi:10.1021/tx900042u
4Zhitkovich A. Nuclear and Cytoplasmic Functions of Vitamin C. Chem Res Toxicol. 2020;33(10):2515-2526. doi:10.1021/acs.chemrestox.0c00348
5Carr A, et al. Does vitamin C act as a pro-oxidant under physiological conditions?. FASEB J. 1999;13(9):1007-1024. doi:10.1096/fasebj.13.9.1007
6Montecinos V, et al. Vitamin C is an. . . stressed human vascular endothelial cells in the presence of a vast molar excess of glutathione. J Biol Chem. 2007;282(21):15506-15515. doi:10.1074/jbc.M608361200
