Article Summary:
- Curcumin, Boswellia, pine bark extracts, glucosamine and chondroitin, vitamin D, and fish oil are known to exert joint support benefits.*
- Poor bioavailability and absorption of many ingredients in joint support supplements adversely affect the efficacy of most formulations.
- Tesseract Medical Research’s advanced nutrient delivery system enables optimal absorption of active nutrients to promote musculoskeletal health.*
The gradual degeneration of joint cartilage and underlying bones that comes with aging is one of the most common causes of stiffness in the knee, hip, and thumb joints. Several other factors contribute to declining joint health, including injuries, long periods of inactivity, and lack of movement. Joint degeneration results in irreversible structural and functional changes in the joints, significantly impacting the quality of life among the aging population.
Oxidative stress–the imbalance between the production of reactive oxygen species (ROS) and their elimination by the body’s antioxidant defense system–is a key underlying cellular mechanism driving joint health decline. Excessive ROS production causes adverse inflammatory responses, resulting in joint swelling and stiffness. Strengthening the body’s antioxidant defense system with a joint support supplement promotes a more healthy musculoskeletal system.*
This post explores the benefits of joint support supplements and why you should consider taking an advanced supplement formulation to promote optimal joint functioning.*
What are Joint Support Supplement Benefits?
Nutritional supplements have been shown1 to exert beneficial effects on bone and joint health.* Various plant extracts, like curcumin, Boswellia, and pine bark extracts, have traditionally been used across cultures for their joint-supportive properties. Additionally, compounds such as glucosamine, chondroitin, vitamin D, and fish oil, are commonly used ingredients in joint support supplements for their proven benefits. The following table highlights how these nutrients provide joint support supplement benefits.*
Joint Support Supplement Benefits |
|
|---|---|
|
Supplement |
Benefits |
|
Curcumin Extracts |
Curcumin, the active compound found in turmeric, has potent antioxidant properties. It modulates several cell signaling pathways to limit adverse immune reactions and maintain the body’s natural inflammatory responses.* These properties of curcumin2 can help address joint and muscle soreness.* |
|
Boswellia Extracts |
The resinous extracts of the Boswellia serrata tree contain different terpenes and triterpenic acid that help maintain bone health.* |
|
Vitamin D |
Maintaining normal bone mineral content is critical in limiting soft bones, muscle weakness, spasms, and cramps.* Vitamin D promotes calcium absorption in the gut and maintains adequate calcium and phosphate serum concentrations to facilitate normal bone mineralization.* |
|
Fish Oil |
Fish oil helps alleviate swollen and tender joints because the omega-3 essential fatty acids in fish oil downregulate natural inflammatory responses through various signaling pathways.* |
|
Glucosamine and Chondroitin |
Chondrocytes are the cells responsible for cartilage formation. Glucosamine and chondroitin, both natural compounds found in cartilage, help maintain a natural inflammatory response, which protects chondrocytes and supports healthy cartilage in the joints.* |
|
Pine Bark Extracts |
Clinical studies3,4,5 suggest that procyanidins extracted from French Maritime pine trees contain water-soluble antioxidants that potentially improve bone remodeling markers and maintain bone mineral density.* |
Achieving the full benefits of joint support supplements depends on the optimal absorption of their active nutrients. For example, curcumin, a potent compound known for its joint-supportive properties, is conventionally difficult for the body to absorb effectively. To maximize its therapeutic benefits, it is recommended to choose an advanced supplement formulation specifically designed to enhance the bioavailability of such nutrients.
Including An Advanced Curcumin Supplement in Your Diet for Joint Support*
The naturally poor bioavailability and absorption of curcumin hinder the efficacy of most curcumin supplements. As a result, a significantly high amount of curcumin must be ingested to achieve its joint support supplement benefits.* In addition, the intense bitter taste of curcumin makes it difficult to ingest orally, which may pose challenges to user compliance.
Tetrahydrocurcumin,a curcumin metabolite, shares similar mechanisms of action with curcumin, but stands out as a more potent antioxidant. This enhanced antioxidant capacity, combined with its immunomodulatory properties, makes tetrahydrocurcumin particularly effective in maintaining normal inflammatory responses and mitigating the adverse effects of oxidative stress on the musculoskeletal system.*
TetraCumin® is an advanced tetrahydrocurcumin formulation developed by Tesseract Medical Research. This breakthrough bioactive formulation transcends curcumin’s naturally poor bioavailability and absorption, as well as its palatability challenges, to provide optimal support for maintaining good musculoskeletal and joint health.*
Tesseract’s proprietary CyLoc® – DexKey® nutrient delivery nanotechnology ensures maximum absorption and enhanced palatability of the tetrahydrocurcumin. The CyLoc® technology encases individual tetrahydrocurcumin molecules to protect their integrity during transit through the stomach. The accompanying DexKey® reactors release the molecules at the desired point in the intestinal tract for optimal absorption.
As a result, tetrahydrocurcumin’s enhanced bioavailability and absorption yield rapid physiological responses to help you achieve the benefits of this advanced joint support supplement.*
The power of Tesseract supplements lies in enhancing palatability, maximizing absorption and bioavailability, and micro-dosing multiple nutrients in a single, highly effective capsule. Shop Productsn our website and learn more about how they support your musculoskeletal health..*
Citations:
1Liu X, et al. Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis. British Journal of Sports Medicine vol. 52,3 (2018):167-175. doi:10.1136/bjsports-2016-097333
2Chin K-Y. The . . . role of curcumin . . . . Drug Design, Development and Therapy vol. 10 3029-3042. 20 Sep. 2016, doi:10.2147/DDDT.S117432
3Huang G, et al. Pycnogenol(®) treatment inhibits bone mineral density loss . . . .” International Journal of Clinical and Experimental Medicine vol. 8,7 10893-901. 15 Jul. 2015
4Panahande SB, et al. Effects of French maritime pine bark extract (Oligopin®) supplementation on bone remodeling markers…. Phytother Res. 2019;33(4):1233-1240. doi:10.1002/ptr.6320
5Salvio G, et al. The Effects of Polyphenols on Bone Metabolism… Antioxidants (Basel). 2023;12(10):1830. doi:10.3390/antiox12101830
