Article Summary:
- Quercetin supplements are commercially available as capsules, tablets, intranasal sprays, topical ointments and sprays, and intravenous drips.
- Quercetin intake through the oral route is characterized by absorption and bioavailability challenges.
- Tesseract’s groundbreaking, proprietary CyLoc® – DexKey® nutrient delivery nanotechnology optimizes the solubility and absorption of quercetin, making it a therapeutic reality.
Quercetin is a plant pigment found in several fruits, vegetables, and grains, including apples, grapes, berries, cherries, onions, broccoli, green tea, and others. Chemically, quercetin is a flavonoid that acts as one of the most potent antioxidants in the diet and promotes various health functions.* Even if you consume 10-100 mg of quercetin daily through different food sources, a quercetin supplement can fill any nutritional gaps.
Oral quercetin supplements in capsule or tablet form are usually preferred over other delivery routes owing to the ease of intake. This article explains everything about quercetin capsules, their uses and benefits, and why you should include an advanced quercetin supplement in your diet.
Quercetin Capsules: An Overview
Quercetin is available in different chemical forms, including glycoside, glucuronide, sulfate, and methylated quercetin. Although quercetin glucoside is relatively more soluble than other forms of quercetin, its bioavailability is still low, highlighting the need for formulated quercetin as an oral supplement.
It is worth noting that the direct extraction of quercetin from natural sources to be used in quercetin capsules or tablets is not feasible owing to its occurrence in various glycosylated forms. Quercetin for supplement formulations is commonly prepared by the acid hydrolysis of rutin — a commodity extracted from different plants.
The following is a brief overview of quercetin supplement formats, including capsules.
Common types of quercetin supplements
Formulated quercetin supplements are commercially available in oral, intravenous, intranasal, and topical formats. Quercetin capsules contain formulated quercetin that displays a significant increase (above 200%) in blood uptake compared to unformulated or free quercetin. A quercetin capsule or a coated tablet typically contains 400 – 600 mg of the active nutrient. Because quercetin displays poor solubility in water, supplement formulations contain additional ingredients, such as vitamin C or bromelain — a protein-digesting enzyme extracted from pineapples – for enhanced absorption.
Benefits of including a quercetin supplement in your diet
The antioxidant properties of quercetin and its role in maintaining the body’s natural inflammatory response promote various health functions inthe heart, kidneys, and immune system.*
- Quercetin and heart health: Quercetin supplementation helps maintain normal systolic blood pressure and enhances endothelium-dependent vasodilation to promote heart health.*
- Quercetin and renal health: Quercetin promotes kidney health by moderating renal toxicity, limiting programmed cell death (apoptosis), and adverse inflammatory responses.*
- Quercetin and immune health: Quercetin inhibits histamine release and down-regulates the production of proinflammatory cytokines and inflammatory mediators (leukotrienes) to better maintain balanced immune responses.*
Side effects of taking a quercetin supplement regularly
The safety profile of quercetin as a dietary supplement is well established. Clinical studies rarely report adverse effects following supplemental quercetin intake. However, it should be noted that the scientific data for safety assessment is only available for short-term intake (up to 12 weeks) of a daily maximum of 1,000 mg of quercetin.
Some animal studies highlight the potential of quercetin to enhance nephrotoxic effects in pre-damaged kidneys. Also, quercetin supplementation might be contraindicated concurrent with prescribed medications for high blood pressure and kidney disorders. It is always recommended to consult your healthcare provider before including a quercetin supplement in your diet.
Absorption challenges associated with quercetin in capsule format
Quercetin displays poor absorption and absorption, which undermines the efficacy of most quercetin capsules. Only 3% – 17% of oral quercetin is estimated to be absorbed in healthy individuals. The poor solubility and absorption of quercetin can be blamed on its low water solubility and instability. The water solubility of quercetin is only 0.01 mg/ml, making it difficult to be absorbed in the gastrointestinal tract.
The absorption challenges of quercetin can be addressed through innovative nutrient delivery systems, including nanocarriers, liposomes, and polymeric micelles.
An Advanced Quercetin Capsule Formulation for Promoting Your Overall Health
Tesseract Medical Research has developed two advanced quercetin proprietary complexes that promote cardiovascular and immune health.* The following factors make the Tesseract formulations superior to other oral quercetin supplements available.
Why is QuerciSorb® the Best Quercetin Supplement? |
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High-quality ingredients: This hypoallergenic, vegetarian formulation for promoting heart health contains solubility-enhanced quercetin from Sophora japonica (flower) concentrate.* | ||
Nutrient delivery nanotechnology: Tesseract’s proprietary CyLoc® – DexKey® nutrient delivery nanotechnology encases individual quercetin molecules in its smart delivery system and releases them at the desired point in the intestinal tract. | ||
Enhanced absorption and bioavailability: The quercetin-loaded nanomolecules are better absorbed and have enhanced bioavailability than free quercetin. | ||
Micro-dosing: The unprecedented absorption of quercetin enables micro-dosing — using a lesser amount of quercetin than previously required to achieve a powerful and prompt physiological response. |
With optimal absorption and bioavailability, Tesseract’s quercetin capsule formultaions provides a powerful and prompt physiological response to better support your cardiovascular and immune health.*
The power of Tesseract supplements lies in enhancing palatability, maximizing bioavailability and absorption, and micro-dosing multiple nutrients in a single, highly effective capsule. Shop products on our website and learn more about how they can help support cardiovascular health.*