Article Summary:
- Lipoic acid is a natural antioxidant synthesized by the mitochondria of the liver and other tissues.
- Lipoic acid’s strong reduction and low oxidation-reduction potential make it one of the most potent cellular oxidation regulators.*
- The enhanced absorption and stability of R-lipoic acid in the plasma results in more pronounced benefits, highlighting its role as a nutritional supplement.
- Tesseract Medical Research’s revolutionary CyLoc® – DexKey® nutrient delivery nanotechnology enhances the bioavailability and absorption of R-lipoic acid to better promote overall health and wellness.
Lipoic acid, also known as alpha-lipoic acid (ALA), is a naturally occurring antioxidant synthesized in the human body. It exists in two chemical forms: R-lipoic acid and S-lipoic acid. Of these, R-lipoic acid is the biologically active form, endogenously produced in the body, and present naturally in many foods. In both animal and plant cells, R-lipoic acid serves as an essential cofactor for mitochondrial enzyme complexes, highlighting its role in cellular energy production.* The extensive biological activities of R-lipoic acid translate to numerous benefits for overall health and wellness.*
Below, we discuss R-lipoic acid’s many benefits and why you should consider an R-lipoic acid supplement in your routine to realize its beneficial potential.
R-Lipoic Acid Benefits — An Overview
The antioxidant properties of R-lipoic acid and its ability to help maintain the body’s natural inflammatory response help mitigate several adverse health conditions characterized by oxidative stress.* The following table highlights the benefits of R-lipoic acid and how it supports various health functions.*
Benefits of R-Lipoic Acid |
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a. Antioxidant support
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b. Immune support
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c. Endocrine health support
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d. Cardiovascular health support
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e. Neurological health support
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The chemical structure of naturally occurring R-lipoic acid in food sources is bound to the amino acid, lysine, within proteins. In contrast, lipoic acid in supplement formulations is not bound to protein, allowing for significantly higher concentrations of this compound compared to dietary sources.
The safety profile of lipoic acid is well-established, with daily doses ranging from 200 mg to 2,400 mg generally being well-tolerated and free from adverse side effects. However, due to limited data available on the prolonged usage and potential contraindications of lipoic acid with prescription medications, it is recommended to consult with your healthcare provider before including a lipoic acid supplement in your routine.
Including An Advanced R-Lipoic Acid Supplement in Your Routine
Tesseract Medical Research’s RLA Pro SR® is an R-lipoic acid formulation developed for optimal bioavailability and absorption. The proprietary CyLoc® – DexKey® nutrient delivery nanotechnology enables unprecedented absorption of R-lipoic acid molecules at the desired point in the intestinal tract to achieve a rapid and powerful physiological response. With micro-dosing in single capsules, RLA Pro SR® helps you realize the benefits of R-lipoic acid to support your overall health and wellness.
The power of Tesseract supplements lies in enhancing palatability, maximizing absorption and bioavailability, and micro-dosing multiple nutrients in a single, highly effective capsule. Shop products on our website and learn more about how they can support your endocrine health.*
Citations:
1Liu W, et al. The immunomodulatory effect of alpha-lipoic acid . . . . BioMed Research International vol. 2019 8086257. 20 Mar. 2019, doi:10.1155/2019/8086257
2Capece U, et al. Alpha-lipoic acid and glucose metabolism: A comprehensive update on biochemical and therapeutic features. Nutrients vol. 15,1 18. 21 Dec. 2022, doi:10.3390/nu15010018
3Khoder NM, et al. Metformin and alpha lipoic acid ameliorate hypothyroidism and its complications in adult male rats. Journal of Diabetes and Metabolic Disorders vol. 21,2 1327-1337. 8 Jun. 2022, doi:10.1007/s40200-022-01063-7
4Hajizadeh-Sharafabad F, et al. Role of alpha-lipoic acid in vascular function: A systematic review of human intervention studies. Critical Reviews in Food Science and Nutrition vol. 62,11 (2022): 2928-2941. doi:10.1080/10408398.2020.1861425