Tetrahydrocurcumin Benefits: How Do They Differ From Curcumin?

Article Summary:

• Tetrahydrocurcumin is a major metabolite of curcumin that exhibits similar properties to curcumin. 
• Tetrahydrocurcumin is known for its enhanced stability and bioavailability, resulting in better absorption than curcumin. 
• The innovative CyLoc – DexKey® nutrient delivery nanotechnology enables optimal absorption of tetrahydrocurcumin to promote various health functions.  

Curcumin is widely recognized for its powerful antioxidant and immunomodulatory properties. However, the low stability and poor systemic bioavailability of curcumin significantly hinders its absorption and effectiveness, posing a challenge for most curcumin nutritional supplements. 

The body breaks down curcumin in the liver before it achieves its active byproduct metabolite, tetrahydrocurcumin (THC), through a process called hydrogenation. As the primary metabolite of curcumin, tetrahydrocurcumin shares many of curcumin’s physiological and pharmacological benefits but stands out as the most potent antioxidant among naturally occurring curcuminoids. With greater stability and bioavailability than curcumin, tetrahydrocurcumin delivers enhanced benefits under physiological conditions, making it a superior option for supporting antioxidant status, immune health, and overall well-being. 

Below, we discuss the benefits of tetrahydrocurcumin, how its benefits differ from curcumin, and why you should include a tetrahydrocurcumin supplement in your diet.   

Why Tetrahydrocurcumin Outshines Curcumin: Key Benefits Explained

The differences in the molecular structures of curcumin and tetrahydrocurcumin result in the functional differences of the two compounds. Tetrahydrocurcumin is more soluble in an aqueous medium, while curcumin is more lipid-soluble. These properties allow THC to achieve high concentrations in the bloodstream and tissues, resulting in higher systemic bioavailability and more pronounced biological effects. The following table summarizes tetrahydrocurcumin’s benefits compared to those of curcumin, highlighting THC’s role as an active ingredient in nutritional supplements.

The body’s inability to convert curcumin into tetrahydrocurcumin rapidly enough results in curcumin being cleared from the bloodstream before it can deliver its full range of benefits. By introducing tetrahydrocurcumin directly into the body, this metabolic conversion step is bypassed, ensuring more effective results.  

Tetrahydrocurcumin is often regarded as a more accessible form of curcumin because of its superior stability and bioavailability, offering enhanced health benefits with greater efficiency. Unlike traditional curcumin supplements, which require higher doses to achieve desired effects, tetrahydrocurcumin supplements provide comparable benefits at much lower quantities. Advanced formulations utilizing nutrient delivery nanotechnology can further enhance the overall solubility and absorption of tetrahydrocurcumin.      

Including A Tetrahydrocurcumin Supplement in Your Diet 

TetraCumin® is an innovative supplement formulation developed by Tesseract Medical Research that achieves the health benefits of tetrahydrocurcumin. Developed in both quick-release and 12-hour sustained-release forms, the formulation promotes joint and muscle health, normal immune function, and a healthy gastrointestinal environment.* 

The proprietary CyLoc® – DexKey® nutrient delivery nanotechnology enables the optimal absorption of tetrahydrocurcumin molecules. The CyLoc® technology encases individual tetrahydrocurcumin molecules in its smart delivery system to maintain their integrity during the transit through the stomach. The accompanying DexKey® reactors release each molecule at the desired point in the intestinal tract for maximum absorption. 

This revolutionary technology accomplishes unprecedented absorption of tetrahydrocurcumin molecules, thereby enabling microdosing of the formulation. With TetraCumin®, you can be assured of optimal absorption of the active nutrient to realize tetrahydrocurcumin’s benefits.