Understanding Turmeric Supplement Benefits

Article Summary:

  • Curcumin, the key ingredient in turmeric supplements, is known for its antioxidant and immunomodulatory properties.* 
  • The poor bioavailability and absorption of curcumin hinder the efficacy of most turmeric supplement formulations.
  • Tesseract’s proprietary CyLoc® – DexKey® nutrient delivery system enables targeted delivery of active nutrients to optimize absorption and achieve turmeric supplement benefits.  

Turmeric is a well-known spice and natural coloring agent that lends a vibrant yellow color to curry recipes. The primary active ingredient in the root of the Curcuma longa plant is curcumin, which gives turmeric its bright yellow color. Curcumin is also known for its antioxidant properties and its ability to help maintain the body’s natural inflammatory response.* Naturally, turmeric supplement benefits make it one of the top-selling nutritional supplements in the United States. 

Below, we discuss various turmeric supplement benefits, how they promote health functions, and why you should include a turmeric supplement in your diet. 

Turmeric Supplement Benefits and How They Support Your Health

Turmeric has been used across different cultures for its therapeutic benefits and has been the subject of multiple scientific studies for decades. The benefits of turmeric supplements are primarily attributed to the antioxidant and immunomodulatory properties of curcumin that mitigate oxidative stress while down-regulating adverse immune responses.*

The following table highlights how turmeric supplements benefit different health functions and promote your overall health and wellness. 


Turmeric Supplement Benefits: An Overview

Joint support
  • The NF-κB cell signaling pathway is at the core of inflammatory responses. Curcumin interacts with several molecular targets, including NF-κB, to address periodic musculoskeletal and joint flare-ups by maintaining a healthy inflammatory response.*  
  • The antioxidant properties of curcumin mitigate oxidative stress, and help limiting the harmful effects of free radicals on bone health.*  

Immune support
  • Curcumin works synergistically with various immune function cells — neutrophils, macrophages, dendritic cells, and natural killer cells, to up-regulate the body’s natural defense capacities.*
  • Curcumin modulates immune cell activities, particularly lowering the level of pro-inflammatory cytokines — the signaling molecules released from immune cells that trigger inflammatory reactions.*  

Cardiovascular support
  • The antioxidant properties of curcumin mitigate oxidative stress in cardiac cells, which is the underlying cause of various adverse heart conditions.* 
  • Some studies1,2,3 associate curcumin’s role in benefiting blood lipid levels to promote healthy cardiovascular function.* 

Gastrointestinal support
  • The antioxidant and immunomodulatory properties of curcumin decrease intestinal permeability, thereby promoting a healthy inflammatory response in the gastrointestinal tract.* 
  • Studies4,5 suggest that curcumin has beneficial effects on gut microbiota by favoring the growth of beneficial bacterial strains.*    

Liver Support
  • Curcumin exerts hepatoprotective effects and limits oxidative stress-induced liver injuries through various cellular and molecular mechanisms.*
  • Curcumin enhances glutathione (GSH) levels by increasing the activity of glutathione S-transferase (GST), thus promoting liver detoxification.*

The health benefits of curcumin are well-established, highlighting the safety of oral intake of turmeric supplements. However, it is always recommended to consult with your healthcare provider before including a turmeric supplement in your diet or taking one concurrent with a prescription medication. 

Curcumin is inherently unstable and displays poor bioavailability, leading to low solubility and absorption, which is why turmeric supplements have been conventionally taken in high amounts to obtain curcumin’s therapeutic benefits. However, the intense bitter taste of curcumin can make it difficult to consume orally, challenging regimen compliance. Tetrahydrocurcumin, a more stable and bioavailable curcumin metabolite, addresses the common challenges associated with curcumin absorption.   

Including A Turmeric Supplement in Your Diet

Tetrahydrocurcumin, the bioactive metabolite of curcumin, displays physiological properties similar to curcumin, but its stability contributes to easy absorption through the gut wall.* TetraCurcumin® is a unique turmeric supplement formulation developed by Tesseract Medical Research for supporting immune function and musculoskeletal health.* 

The TetraCurcumin formulation contains tetrahydrocurcumin and utilizes the proprietary CyLoc® – DexKey® nutrient delivery nanotechnology to mask the unpalatable taste and ensure targeted delivery of the active nutrient at the desired point in the intestinal tract. The unprecedented absorption of tetrahydrocurcumin in the formulation allows for micro-dosing — using lesser amounts of the active ingredient than previously required to achieve the desired result in your joints and immune system.* 

The power of Tesseract supplements lies in enhancing palatability, maximizing absorption and bioavailability, and micro-dosing a single or multiple nutrients in a single, highly effective capsule. Shop products on our website and learn more about how they can support your immune health.*

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Citations:

1Cox FF, et al. Cells vol. 11,3 342. 20 Jan. 2022, doi:10.3390/cells11030342

2Rafiee S et al. Adv Exp Med Biol. 2021;1291:165-177. doi:10.1007/978-3-030-56153-6_10

3Musazadeh V et al. Nutr Metab Cardiovasc Dis. 2022;32(11):2493-2504. doi:10.1016/j.numecd.2022.07.021

4Scazzocchio B, et al. Nutrients vol. 12,9 2499. 19 Aug. 2020, doi:10.3390/nu12092499

5He Y et al. Am J Clin Nutr. 2024;120(1):66-79. doi:10.1016/j.ajcnut.2024.05.017

Al Czap, Founder | Tesseract

Al Czap has more than four decades of professional experience in preventative medicine. He founded Thorne Research in 1984 (sold in 2010) and he published Alternative Medicine Review for 17 years beginning in 1996. AMR was a highly acclaimed, peer-reviewed, and indexed medical journal. Al was the first to recognize the need for hypoallergenic ingredients and to devise methods of manufacture for and delivery of hypoallergenic products to underserved patient populations. His work has greatly impacted those with impaired immune and digestive systems and compromised health due to environmental exposures.

The advanced formulations based on our revolutionary, patented, and patent-pending technology are only available through Tesseract. No other medical, pharmaceutical, or supplement company is licensed to utilize our proprietary technology.
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
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