Bioavailable Nutrients: The Key to Advanced Supplements

Article Summary:

• The bioavailability of a nutrient depends on several factors, including the food source, the matrix in which it is consumed, and the composition of the whole meal. 
• Advanced delivery technologies, such as microcapsules, nanoparticles, and cyclodextrin inclusion compounds, enhance nutrient absorption and bioavailability. 
• Tesseract’s proprietary nutrient delivery nanotechnology enhances the bioavailability of difficult-to-absorb nutrients, such as glutathione, berberine, and curcumin.

Bioavailability refers to the proportion of a nutrient that is digested, absorbed, and metabolized through normal body pathways. Knowing how much of a nutrient is present in a nutritional supplement is not enough; it is also important to know how much of the nutrient present is bioavailable. Nutrient bioavailability directly impacts the efficacy of the supplement formulation. Hence, selecting a nutritional supplement that contains bioavailable nutrients is critical to achieving its associated health benefits. 

This post explains how bioavailable nutrients make superior supplement formulations, enable micro-dosing, and why you should consider an advanced supplement formulation with bioavailable nutrients. 

The Role of Bioavailable Nutrients in Making Advanced Supplement Formulations 

A common myth regarding the bioavailability of nutritional supplements is that they should be in a solution to be better absorbed. Notably, nutrients react differently after they have been ingested, and their absorption can be influenced by several factors, including: 

• The quality of the food source
• The matrix in which the nutrient is consumed
• The composition of the whole meal, inhibitors, and enhancers
• The health status of the host

The bioavailability of a nutrient quantifies the amount entering the bloodstream. After a nutrient is in the bloodstream, it should cross the targeted cell membranes to exert its intended beneficial effects. While low absorption and bioavailability of certain nutrients can adversely affect their therapeutic potential, they can also cause adverse side effects. 

Iron is a typical example of poor nutrient absorption and low bioavailability that can cause unpleasant side effects. When taking an iron supplement, an individual with an inflamed gut condition can experience constipation, bloating, abdominal pain, or other gastrointestinal side effects. Unabsorbed iron can remain in the gut, resulting in gastrointestinal disturbances. Additionally, plant-based non-heme iron requires vitamin C to be more optimally absorbed. Hence, a more bioavailable form of iron would help prevent such adverse gastrointestinal effects and low absorption. 

The following table highlights how bioavailable nutrients make better nutritional supplement formulations. 

The absorption and bioavailability of the nutrients in a nutritional supplement depend on how well it is formulated. Conventional supplement formulations often fail to enhance the bioavailability of the active nutrients. Because of this shortcoming, various novel pharmacological approaches are being used to enhance nutrient bioavailability, including:

• Microcapsules
• Solid dispersion systems
• Nanoparticles
• Nano-liposomes
• Cyclodextrin inclusion compounds

An advanced supplement formulation that utilizes these novel techniques enhances the bioavailability of nutrients to improve its therapeutic potential.  

Including An Advanced Supplement Formulation in Your Diet 

Tesseract Medical Research utilizes the proprietary CyLoc® —DexKey® nutrient delivery nanotechnology to enhance the absorption and bioavailability of nutrients that have been traditionally difficult to absorb (glutathione) or impossible to tolerate (berberine and curcumin). The CyLoc® technology surrounds each insoluble and poorly absorbed nutrient molecule in its smart delivery system to maintain its integrity during transit through the stomach. The accompanying DexKey® reactors release each nutrient molecule at the desired point in the intestinal tract to enhance its absorption and bioavailability.  

Tesseract supplements are formulated with trusted nutrients that have substantial therapeutic potential. Each Tesseract supplement formulation is developed using scientifically advanced analytical techniques and quality control systems that adhere to the best manufacturing standards. 

Tesseract’s proprietary nutrient delivery technology enables maximum solubility and effectiveness of nutrient molecules, which aligns with Tesseract’s three-pillar approach: optimal absorption, enhanced palatability, and micro-dosing. The unprecedented absorption of bioavailable nutrients makes Tesseract formulations among the best commercially available nutritional supplements.