Benefits of Glutathione Supplementation

Article Summary:

  • Supplementing with glutathione supports healthy aging by maintaining healthy nervous system function, promoting gut and immune health, balancing the endocrine system, and enhancing skin and hair vitality1
  • Although intravenous or intramuscular glutathione injections display better absorption of glutathione than their oral counterparts, oral supplements are generally more convenient to take and integrate into a daily routine. 
  • Tesseract’s unique glutathione supplement formulation uses CyLoc® – DexKey® nutrient delivery nanotechnology to enhance glutathione’s palatability, absorption, and bioavailability. 

The aging process is typically associated with the body’s increased production of reactive oxygen species (ROS). Excessive ROS causes oxidative stress and can severely damage cellular components, including DNA, lipids, proteins, and organelle membranes. The decline in the body’s natural antioxidant defense system and the damage caused by ROS contribute negatively to the aging process. 

Glutathione, a potent antioxidant, is present in every cell in the body and is crucial for eliminating ROS and mitigating oxidative stress2. Glutathione’s critical role as a detoxifying agent and free radical scavenger is why it is often referred to as the body’s ‘master antioxidant.’ Impairment of glutathione’s function in the brain is linked to the loss of neurons during the aging process, which can result in neurological disorders3. A low level of glutathione is also associated with deteriorating gastrointestinal health and endocrine health, as well as less-than-healthy skin and hair4.

One of the best ways to enhance depleted glutathione levels is by including a glutathione supplement in your regular health routine. Let’s further examine the benefits of glutathione supplementation and why you should include an advanced glutathione formulation to support healthy aging.*

What are Glutathione Supplement Benefits? 

Glutathione supplements vary in mode of delivery, which include oral, intranasal, intravenous/intramuscular, and nebulized modes. 

The following table highlights glutathione supplement benefits and how they promote various health functions:

Benefits of Glutathione Supplementation
Health Function Benefits
Nervous system*
Glutathione supplementation provides neuronal defense against damage caused by free radicals.*5
Gastrointestinal system* Research indicates a direct correlation between a low glutathione concentration and mucosal damage in various adverse conditions of the gastrointestinal tract.*
A glutathione supplement protects mucosal cells in the gastrointestinal tract from oxidative stress.*6
Immune Function* Glutathione supplements help maintain a delicately balanced intermediate glutathione level in lymphoid cells for optimal immune function.*7 
Endocrine System* As a detoxifying agent and antioxidant, glutathione protects the liver from oxidative stress.*8
Glutathione can reduce elevated liver enzymes and support hepatic metabolism.*9
Skin and Hair  Topical and intravenous glutathione promote healthy skin and hair via their antioxidant mechanisms.10

Alternative delivery methods, such as intravenous or intramuscular glutathione injections, bypass the absorption of glutathione in the gastrointestinal tract, allowing it to enter the bloodstream directly. Although these injections are particularly popular for skin care and wellness applications, IV glutathione drips require medical supervision and sometimes aren’t compatible with certain health conditions.

When considering adding an oral glutathione supplement to your diet, you should select an advanced formulation that ensures optimal bioavailability and absorption.  

Incorporating an Advanced Glutathione Supplement Into Your Diet

Tesseract Medical Research’s SafeCell® is a unique glutathione supplement formulation that solves the challenges of glutathione’s palatability, bioavailability, and absorption. 

SafeCell’s acetylated form of glutathione formula utilizes Tesseract’s proprietary CyLoc® – DexKey® nutrient delivery nanotechnology that enables unprecedented absorption of glutathione. SafeCell promotes the optimal functioning of other antioxidants, supports natural detoxification pathways, down-regulates oxidative stress, and supports optimal cellular and neurological function because it can readily cross the blood-brain barrier.* 

The Tesseract Detoxification Solution helps you maintain optimal health as you age.*

The power of Tesseract supplements lies in enhancing palatability, maximizing solubility, bioavailability and absorption, and micro-dosing of multiple nutrients in a single, highly effective capsule. Shop products on our website and learn more about how they support healthy aging.*

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References:

1Sekhar, Rajagopal V et al. The American journal of clinical nutrition vol. 94,3 (2011): 847-53. doi:10.3945/ajcn.110.003483

2,3Kwon, Da Hye et al. Antioxidants (Basel, Switzerland) vol. 8,4 82. 1 Apr. 2019, doi:10.3390/antiox8040082

4Pizzorno, Joseph. “Glutathione!.” Integrative medicine (Encinitas, Calif.) vol. 13,1 (2014): 8-12.

5Park MK, et al. International Journal of Molecular Sciences vol. 24,3 2950. 2 Feb 2023, doi:10.3390/ijms24032950

6Bhattacharyya A, et al. Physiological Reviews vol. 94,2(2014):329-354. doi:10.1152/physrev.00040.2012

7Dröge W, Breitkreutz R. The Proceedings of the Nutrition Society vol. 59,4(2000):595-600. doi:10.1017/s0029665100000847

8Vairetti M, et al. Antioxidants (Basel, Switzerland) vol. 10,3 364. 28 Feb 2021, doi:10.3390/antiox10030364

9Honda Y, et al. BMC Gastroenterology vol. 17,1 96. 8 Aug 2017, doi:10.1186/s12876-017-0652-3

10Weschawalit S, et al. Clinical, Cosmetic and Investigational Dermatology vol. 10 147-153. 27 Apr 2017, doi:10.2147/CCID.S128339

Al Czap, Founder | Tesseract

Al Czap has more than four decades of professional experience in preventative medicine. He founded Thorne Research in 1984 (sold in 2010) and he published Alternative Medicine Review for 17 years beginning in 1996. AMR was a highly acclaimed, peer-reviewed, and indexed medical journal. Al was the first to recognize the need for hypoallergenic ingredients and to devise methods of manufacture for and delivery of hypoallergenic products to underserved patient populations. His work has greatly impacted those with impaired immune and digestive systems and compromised health due to environmental exposures.

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