Chemical formula of glutathione

Glutathione Supplement Benefits

Article Summary:

  • Glutathione supplementation supports a wide range of health functions, in the nervous system, the gastrointestinal system, immune function, the endocrine system, as well as skin and hair health.* 
  • Although intravenous or intramuscular glutathione injections provide better absorption of glutathione than their oral counterparts, these injections require medical supervision and might not be compatible with certain health conditions. 
  • Tesseract’s unique glutathione supplement formulation uses CyLoc® – DexKey® nutrient delivery nanotechnology to enhance glutathione’s palatability, absorption and bioavailability. 

The aging process is typically associated with increased production of reactive oxygen species (ROS) in the body. Excessive ROS  cause oxidative stress and can severely damage cellular components, including DNA, lipids, proteins, and organelle membranes. The decline in the body’s natural antioxidant defense system and the damage caused by ROS contribute to the aging process. 

Glutathione, which acts as an antioxidant, is present in every body cell and is crucial in eliminating ROS and addressing oxidative stress.* Glutathione’s critical role as a detoxifying agent and free radical scavenger is why it is often referred to as the master antioxidant. Impairment of glutathione function in the brain is linked to the loss of neurons during the aging process and can result in  neurological disorders. Low levels of glutathione have also been associated with deteriorating gastrointestinal (GI) and endocrine health, as well as the health of skin and hair. 

One of the best ways to enhance depleted glutathione levels in the body is by including a glutathione supplement in your regular diet. Let’s examine the benefits of glutathione supplements and why you should include an advanced formulation to support healthy aging.*  

What Are Glutathione Supplement Benefits? 

Glutathione supplements vary based on the mode of delivery, including oral, intranasal, intravenous/intramuscular, and nebulized. The following table highlights the benefits of glutathione supplements and how they promote various health functions.*

Benefits of Glutathione Supplementation

Health Function

Benefits

Nervous system*


  • Glutathione supplementation provides neuronal defense against damage caused by free radicals.1

Gastrointestinal system*

  • Several studies indicate a direct correlation between low glutathione concentration and mucosal damage in various adverse conditions of the GI tract.2
  • Glutathione supplements protect mucosal cells in the GI tract from oxidative stress.3

Immune Function*

  • Glutathione supplements help maintain a delicately balanced intermediate glutathione level in lymphoid cells for optimal immune system functioning.4 

Endocrine System*

  • As a detoxifying agent and antioxidant, glutathione protects the liver from oxidative stress.5
  • Glutathione can help reduce elevated liver enzymes and support hepatic metabolism.6

Skin and Hair 

  • Topical and intravenous glutathione supplements can help promote healthy skin and hair via their antioxidant mechanisms.7

Although oral glutathione is the most popular delivery method for glutathione supplementation, it has not been always considered the most effective. The rapid absorption of oral glutathione in the gastrointestinal tract and its poor bioavailability are the key factors contributing to the low efficacy of oral glutathione supplements. 

Alternative delivery methods, such as intravenous or intramuscular glutathione injections, have been explored because they bypass the absorption of glutathione in the gastrointestinal tract, allowing it to directly  enter the bloodstream . These injections are particularly trending for skin care and wellness applications. However, IV glutathione drips require medical supervision and might not be compatible with certain health conditions.

When considering adding an oral glutathione supplement to your diet, it is worth selecting an advanced formulation that ensures optimal bioavailability and absorption.  

Incorporating An Advanced Glutathione Supplement Into Your Diet

Tesseract Medical Research’s SafeCell® is a unique supplement formulation that solves the common challenges of palatability, bioavailability, and absorption of glutathione. SafeCell’s acetylated form of glutathione formula utilizes the proprietary CyLoc® – DexKey® nutrient delivery technology that enables unprecedented absorption of glutathione. SafeCell promotes the optimal functioning of other antioxidants, supports natural detoxification pathways, modulates oxidative stress, and because it crosses the blood-brain barrier, it supports optimal cellular and neurological function.* The Tesseract Detoxification Solution helps you maintain optimal health as we age.*

The power of Tesseract supplements lies in enhancing palatability, maximizing bioavailability and absorption, and micro-dosing of multiple nutrients in a single, highly effective capsule. Shop products on our website and learn more about how they can help support healthy aging.* 

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Citations:

1Park, Min Kyu et al. International journal of molecular sciences vol. 24,3 2950. 2 Feb. 2023, doi:10.3390/ijms24032950

2Loguercio C, Di Pierro M. Italian journal of gastroenterology and hepatology vol. 31,5 (1999): 401-407.

3Bhattacharyya, Asima et al. Physiological reviews vol. 94,2 (2014): 329-54. doi:10.1152/physrev.00040.2012

4Dröge, W, and R Breitkreutz. “Glutathione and immune function.” The Proceedings of the Nutrition Society vol. 59,4 (2000): 595-600. doi:10.1017/s0029665100000847

5Vairetti, Mariapia et al. Antioxidants (Basel, Switzerland) vol. 10,3 364. 28 Feb. 2021, doi:10.3390/antiox10030364

6Honda, Yasushi et al. BMC gastroenterology vol. 17,1 96. 8 Aug. 2017, doi:10.1186/s12876-017-0652-3

7Weschawalit, Sinee et al. “Glutathione and its antiaging and antimelanogenic effects.” Clinical, cosmetic and investigational dermatology vol. 10 147-153. 27 Apr. 2017, doi:10.2147/CCID.S128339

Al Czap, Founder | Tesseract

Al Czap has more than four decades of professional experience in preventative medicine. He founded Thorne Research in 1984 (sold in 2010) and he published Alternative Medicine Review for 17 years beginning in 1996. AMR was a highly acclaimed, peer-reviewed, and indexed medical journal. Al was the first to recognize the need for hypoallergenic ingredients and to devise methods of manufacture for and delivery of hypoallergenic products to underserved patient populations. His work has greatly impacted those with impaired immune and digestive systems and compromised health due to environmental exposures.

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