Red and white blood cells in the vein.

The Best Circulation Support Supplements

The cardiovascular system comprises the heart, arteries, veins, and capillaries and provides blood supply throughout the body. The parasympathetic and sympathetic nervous systems help the circulatory system respond to various stimuli to control the amount and velocity of blood carried through the vessels. 

Various factors, such as genetic conditions, infections, lifestyle, and aging, can impact the optimal functioning of the circulatory system. Circulatory dysfunction adversely affects the heart and blood vessels, restricts blood flow throughout the body, and can be the underlying cause of several cardiovascular conditions. 

In this post, we discuss the circulatory system, factors that affect its functions, how certain nutrients can support it, and why you should include the best circulation supplements in your diet to promote heart health. Use the links below to jump ahead to different topics on the page.

Circulatory System: An OverviewRisk Factors Affecting Circulatory Functions 
Best Circulation Support Supplements: How They Promote Cardiovascular HealthIncluding an Advanced Circulation Supplement in Your Diet
FAQs: Frequently Asked Questions About Circulation Support Supplements

Cardiovascular System: An Overview

Flow of red blood cells into the blood vessel.

The cardiovascular system is categorized into two loops: 

  • Systemic circulation: It allows oxygenated blood and nutrients to reach the rest of the body. 
  • Pulmonary circulation: It allows the oxygenation of the blood. 

Let’s understand how the various components of the cardiovascular system work. 

  • Heart: It pumps blood through the vessels directly into the arteries, particularly the aorta or the pulmonary artery. 
  • Blood vessels: These include the arteries, veins, and capillaries. 
  • Arteries: They carry blood away from the heart and are divided into large and small arteries. Large arteries receive the highest blood flow pressure and are, hence, thicker and more elastic. 

Smaller arteries, such as arterioles, have more smooth muscles for contraction and relaxation to regulate blood flow to different body parts. Arterioles face relatively smaller blood pressure and account for most of the resistance in the pulmonary circulation.  

  • Veins: Veins transport blood back to the heart and contain valves to prevent the backflow of blood. 
  • Capillaries: Capillaries branch off of arterioles and are a single-cell layer that exchanges nutrients, gases, and wastes with tissues and organs. 

Further, micro-circulation consists of a network of small blood vessels—arteries, arterioles, capillaries, venules, and veins. The micro-circulatory network, along with the interstitium and lymphatic vessels, helps maintain the homeostasis of tissues and the entire circulatory system. 

Risk Factors Affecting Cardiovascular Functions

Several risk factors can affect the optimal functioning of the cardiovascular system and accordingly increase the risks of adverse cardiovascular conditions. The following table highlights various risk factors that can compromise the cardiovascular system.

Risk Factors Affecting Cardiovascular Functions
  • Health conditions: Health conditions, such as high blood pressure and unhealthy cholesterol levels, pose risks to the circulatory system. 

    High blood pressure refers to the elevated pressure of the blood in arteries and other blood vessels. If not controlled, then it can damage the vital organs, including the heart, kidneys, and brain. Unhealthy blood cholesterol levels can cause narrowing of the arteries and decrease blood flow to other parts of the body.

    Various metabolic conditions, such as high blood glucose levels and unhealthy weight management, can also adversely affect the circulatory system.
  • Lifestyle: Eating a diet high in saturated fats, trans fats, cholesterol, and salt is linked to adverse heart conditions. Increased intake of alcohol and tobacco use raises blood pressure levels and has negative impacts on circulatory functions. 

    A sedentary lifestyle increases the chances of high blood pressure, high cholesterol levels, and high blood glucose levels, which, in turn, adversely affect cardiovascular functions.
  • Other factors: Factors such as genetics and family history, race and ethnicity, age, and gender also play a role in conditions that can adversely affect the circulatory system. When combined with unhealthy lifestyle choices, these factors elevate the risks of unhealthy cardiovascular conditions.

Best Circulation Support Supplements: How They Promote Cardiovascular Health

Food sources to support heart health.

Your dietary choices significantly impact your cardiovascular system. Food sources that are high in sodium, sugar, unhealthy fats, and low in fiber can compromise venous function.1 A balanced diet for circulatory health should consist of fruits and vegetables, fiber-rich foods, and foods that contain omega-3 fatty acids and vitamin E. Adequate hydration is also critical to maintaining cardiovascular health. 

A research study has highlighted that nutritional supplements, such as folate, omega-3 fatty acids, vitamin D, and calcium, are beneficial for achieving positive cardiovascular outcomes.2 Furthermore, regular intake of probiotics enhances cardiovascular health by minimizing oxidative stress. 

The following table highlights several key nutrients that support circulation, the food sources that are rich in those nutrients, and their benefits. 

Best Circulation Support Supplements, Their Food Sources, and Benefits
  • The B Vitamin Family (B1, B6, B12, and Folic Acid)
  • B vitamins are water-soluble vitamins found in various foods, including fortified cereals, whole grains, lentils, bananas, liver, shellfish, and eggs.
  • Vitamin B1 promotes better blood circulation through endothelium-dependent vasodilation — the widening of arteries and veins.
  • Vitamins B6 and B12 minimize instances of blood clot formation in veins.
  • Folic acid enhances endothelium-dependent vasodilation in the peripheral circulation.
  • Vitamin C
  • Citrus fruits, bell peppers, cherries, tomatoes, cruciferous vegetables, and white potatoes are rich sources of vitamin C.
  • Vitamin C is an antioxidant that protects vascular vessels from the harmful effects of oxidative stress.
  • Vitamin E
  • Vitamin E, a fat-soluble vitamin, is contained in various fruits, vegetables, nuts, seeds, and cooking oils, including wheat germ oil, sunflower seeds, soybean oil, pumpkin, red bell peppers, spinach, and avocado.
  • Vitamin E helps modulate multiple molecular mechanisms, limiting blood clot formation within veins and arteries and maintaining a natural inflammatory response in blood vessels.
  • Citrulline
  • Citrulline is an amino acid found in pumpkin, squash, cucumber, melons, and watermelon.
  • Citrulline enhances L-arginine and nitric oxide (NO) levels, which increases blood flow and induces vasodilation.
  • CoQ10 is a fat-soluble compound synthesized in animal tissues. Food sources rich in CoQ10 include oily fish, organ meats, and whole grains.
  • CoQ10 acts as an antioxidant to resist aging and the dysfunction caused by oxidative stress in vascular endothelial cells.
  • CoQ10 supplementation helps alleviate various adverse health conditions associated with blood vessel dysfunction or insufficiencies.
  • Vegetables like broccoli, spinach, Brussels sprouts, tomatoes, red meat, and organ meats are rich in the naturally occurring compound lipoic acid.
  • Lipoic acid enhances endothelial function by increasing the bioavailability of endothelium-derived NO and functioning as an antioxidant by limiting oxidative stress and adverse inflammatory reactions.
  • Is an enzyme released by bacteria during the fermentation of soybeans. The traditional Japanese meal of fermented soybeans is the richest source of nattokinase.
  • Nattokinase supplementation helps limit hardening and narrowing of arteries, restricts the formation of blood clots, and lowers blood pressure.

Although these nutrients can be obtained in the diet, nutritional supplements are also a suitable alternative for obtaining them to further support a healthy cardiovascular system.* 

Including An Advanced Circulation Support Supplement in Your Diet

NOX Flo SRTM is an advanced cardiovascular health supplement developed by Tesseract Medical Research. It contains clinically validated rutinosides, Hesperidin 2S, and Diosmin citrus flavonoids, along with citrulline, Coenzyme Q10, and R-lipoic acid, for enhancing NO synthesis and NO-dependent endothelial function and vasodilation.* 

NattoGuard is an innovative circulation support supplement that contains nattokinase and two plant terpenes: borneol and trans-cinnamaldehyde. The hypoallergenic formulation has cardioprotective properties that optimize the functioning of the circulatory system.*   

The potent blend of nutrients in each of the above supplement formulations is powered by Tesseract’s proprietary CyLoc® —DexKey® nutrient delivery nanotechnology, which ensures optimal nutrient bioavailability and absorption. 

These groundbreaking circulation support supplements display unprecedented absorption of their active nutrients, which provides nutritional support to individuals experiencing compromised endothelial function and vascular insufficiencies.*

Frequently Asked Questions About Circulation Support Supplements

Here are some frequently asked questions (FAQs) about circulation support supplements. 

Can I take a circulation support supplement with prescribed medicines?

Although the health-promoting benefits of circulation support supplements are well-established, there is a potential for additive effects and a limited understanding of potential contraindications and side effects associated with taking them with prescription medications. Consult your healthcare provider before including a circulation support supplement in your diet or taking one with prescription medications. 

What should I look for when considering the best circulation support supplements?

The efficacy of a nutritional supplement depends on the active nutrients in the formulation and their having optimal absorption and bioavailability. When considering the best circulation support supplement, you should look for the desired ingredient as the active nutrient in the formulation and an advanced nutrient delivery technology that ensures the optimal absorption and bioavailability of the active ingredient.  

The power of Tesseract supplements lies in enhancing palatability, maximizing solubility, absorption and bioavailability, and micro-dosing multiple nutrients in a single, highly effective capsule. Shop products on our website and learn more about how they can support your circulatory health.*

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Citations: 

1He J, Ma F, Yao J, et al. Ann Vasc Surg 2023;88:257-267. doi:10.1016/j.avsg.2022.06.015

2Khan SU, et al. Annals of Internal Medicine vol. 171,3 (2019):190-198. doi:10.7326/M19-0341

3Arora S, et al. Annals of Vascular Surgery vol. 20,5 (2006):653-658. doi:10.1007/s10016-006-9055-6

4Ren J, et al. Ecotoxicology and Environmental Safety vol. 241 (2022):113735. doi:10.1016/j.ecoenv.2022.113735

5Garg A, Lee JC-Y. Life (Basel, Switzerland) vol. 12,2 310. 18 Feb. 2022, doi:10.3390/life12020310

6Miyatake S, et al. Biochemistry and Biophysics Reports vol. 28 101149. 8 Oct. 2021, doi:10.1016/j.bbrep.2021.101149

7Zozina VI, et al. Current Cardiology Reviews vol. 14,3 (2018):164-174. doi:10.2174/1573403X14666180416115428

8Hajizadeh-Sharafabad F, Zahabi ES. Critical Reviews in Food Science and Nutrition vol. 62,11 (2022):2928-2941. doi:10.1080/10408398.2020.1861425

9Chen H, et al. Biomarker Insights vol. 13 1177271918785130. 5 Jul. 2018, doi:10.1177/1177271918785130

Al Czap, Founder | Tesseract

Al Czap has more than four decades of professional experience in preventative medicine. He founded Thorne Research in 1984 (sold in 2010) and he published Alternative Medicine Review for 17 years beginning in 1996. AMR was a highly acclaimed, peer-reviewed, and indexed medical journal. Al was the first to recognize the need for hypoallergenic ingredients and to devise methods of manufacture for and delivery of hypoallergenic products to underserved patient populations. His work has greatly impacted those with impaired immune and digestive systems and compromised health due to environmental exposures.

The advanced formulations based on our revolutionary, patented, and patent-pending technology are only available through Tesseract. No other medical, pharmaceutical, or supplement company is licensed to utilize our proprietary technology.
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
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