Article Summary:
- Vitamins, minerals, and other natural compounds, such as anandamide, N-acetyl-L-leucine, butyric acid, and glutathione, are some of the most effective supplements for supporting nerve health.*
- A majority of nerve health support supplements are unable to achieve the optimal absorption and bioavailability of active nutrients.
- Tesseract’s proprietary nutrient delivery nanotechnology enables targeted delivery of active nutrients at the desired point in the intestinal tract for maximum solubility.
As oxidative stress increases with age in our bodies, our nervous systems become more vulnerable to damage, leading to a decline in nerve health. The increased production of reactive oxygen species (ROS) causes neuroinflammation, a contributor of nerve pain. Prolonged nerve pain can indicate malfunctioning of the nervous system and eventually cause nerve damage.
Research indicates that a healthy diet accompanied by moderate exercise promotes a healthy nervous system. Different types of diets, such as the Mediterranean, DASH (Dietary Approaches to Stop Hypertension), and MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay) diets, all exert beneficial effects on protecting neuronal function.
Specific nutritional gaps in the diet can be filled in with supplements. In this post, we discuss some key nutritional supplements that support nerve health and why you should consider an advanced supplement formulation for supporting the health of your nervous system.
Nutritional Supplements that Support Nerve Health: An Overview
Did you know that nerve pain affects 7-10 percent of U.S. adults? When pharmacologic approaches do not provide the desired relief, individuals experiencing nerve pain look for alternatives. Nutritional supplements, such as vitamins (vitamins B and vitamin D), minerals (zinc and magnesium), and other natural compounds (anandamide, N-acetyl-L-leucine (NALL), butyric acid, and glutathione), promote nerve health and help manage pain.*
The following table highlights some of the supplements that can support nerve health and enhance cognitive function.
| Nutritional Supplements that Support Nerve Health: An Overview | |
|---|---|
| Vitamin B complex: The neurotropic B vitamins – B1, B6, and B12 – are critical for maintaining good neurological health.* The synergistic interaction of these vitamins enhances motor control and neural processes and helps manage nerve pain.*1 | |
| Vitamin D: The correlation between nerve pain and a low vitamin D level in individuals experiencing high blood glucose levels indicates vitamin D’s potential role in maintaining nerve health.*2 | |
| Omega-3 fatty acids: Omega-3 fatty acids play an essential role in neuroinflammation, neurogenesis, and neurotransmission. Omega-3 fatty acids down-regulate inflammatory processes and help maintain nerve health, and their deficiency can cause several adverse neurological conditions.*3 | |
| Anandamide: Anandamide-mediated signaling at peripheral cannabinoid type 1 (CB1) receptors can down-regulate the access of pain-related inputs to the central nervous system. The potential role of anandamide in mitigating pain initiation through the peripheral endocannabinoid system offers a new approach to addressing nerve pain.*4 | |
| N-acetyl-L-leucine (NALL): L-leucine exerts neuroprotective effects and protects against age-associated decline of memory and cognitive function. Insufficient levels of this branched-chain amino acid exacerbated cognitive impairment in animal models.5 | |
| Butyric Acid: Postbiotic nutrients, such as butyric acid, support neurological health by countering the gastrointestinal disturbance caused by certain imbalances in the microbiome.*6 | |
| Glutathione: Glutathione protects against ROS and toxic xenobiotics in the central nervous system. Imbalanced glutathione homeostasis leads to an impaired antioxidant defense system, which, in turn, is associated with adverse neurodegenerative conditions.*7 |
Including An Advanced Neurological Support Supplement in Your Diet
An advanced neurological support supplement will utilize innovative nutrient delivery nanotechnology to enhance the absorption and bioavailability of nutrients. The following are some of the best nutritional supplements for supporting nerve health developed by Tesseract Medical Research.
AnaQuell® is an innovative nutritional supplement formulation that supports the body’s natural response to stress and anxiousness.* In particular, the combination of anandamide and L-citrulline in AnaQuell’s proprietary complex supports a healthy response to mood changes and mild non-GAD anxiety.*
AuRx® is an advanced butyric acid formulation that addresses a specific nutritional requirement of children with ASD. This hypoallergenic medical food is a stabilized butyric acid complex that provides nutritional support to counteract a specific gut-brain nutrient imbalance observed in children affected with ASD.
SafeCell® is an acetylated glutathione formula that solves glutathione’s natural bioavailability and absorption challenges to achieve its benefits for promoting nerve health.*
These Tesseract formulations all contain the proprietary CyLoc® – DexKey® nutrient delivery nanotechnology. The CyLoc® technology encases each nutrient molecule in its own dextrin fiber delivery cage. The DexKey® technology accompanies each CyLoc® molecule and breaks the dextrin fiber cage at the desired point in the intestinal tract for the optimal absorption and bioavailability of the active nutrient molecules.
The power of Tesseract supplements lies in enhancing palatability, maximizing solubility, absorption, and bioavailability, and micro-dosing multiple nutrients in a single, highly effective capsule. Shop productson our website and learn more about how they support neurological health.*
References:
1Rayner MLD, et al. In Vitro Cellular & Developmental Biology. Animal vol. 61,3 (2025):264-267. doi:10.1007/s11626-025-01024-3
2Hong S-H, et al. Endocrinology and Metabolism (Seoul, Korea) vol. 36,1 (2021):106-113. doi:10.3803/EnM.2020.826
3Zhang AC, et al. BMJ Open vol. 8,3 e020804. 25 Mar. 2018, doi:10.1136/bmjopen-2017-020804
4Clapper JR, et al. Nature Neuroscience vol. 13,10 (2010):1265-1270. doi:10.1038/nn.2632
